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Expert Bracket Picks: Bet South Dakota State ATS vs Iowa State

No. 2 seed Iowa State is a 16 ½-point favorite against No. 15 South Dakota State in the March Madness matchup. The over-under is set at 135 ½ points.

Thursday’s opening round begins the long road to the men’s Final Four schedule that runs from April 6-8. Let’s take a look at our betting breakdown of the Iowa State-South Dakota State matchup.

Expert Bracket Picks: Bet South Dakota State ATS vs Iowa State
Expert Bracket Picks: Bet South Dakota State ATS vs Iowa State


South Dakota State vs Iowa State Game Information

  • Game: South Dakota State (22-12) vs Iowa State (27-7)
  • Date/Time: Thursday, March 21, 7:35 p.m. ET
  • Location: CHI Health Center, Omaha, Neb.
  • South Dakota State vs Iowa State Live Stream: TBS.com


No. 15 seed South Dakota State (22-12) is a 16½ -point dog against No. 2 seed Iowa State (27-7) in the college basketball odds. This NCAA tournament matchup tips off on Thursday, March 21 at 9:30 p.m. ET. Fans can watch the game on TruTV or stream via the March Madness app.


South Dakota State vs Iowa State Odds and Spreads


  • Iowa State has been on fire at the window going 22-10-2 against the spread.
  • South Dakota State is 17-14 ATS this season in the NCAAB odds.
  • The Cyclones are 22-3 straight up as a favorite.
  • South Dakota State’s games have gone under in six straight matchups when the team is an underdog of 13 points or greater.
  • Iowa State has gone under in 18 games, while the over has hit 16 times.
  • The Jackrabbits have split the over-under equally at 15 games each this season.
  • The Cyclones have gone under in their last five March Madness games.
  • South Dakota State’s last five games have gone under.



South Dakota State vs Iowa State Over/Under Pick: Under 135½

Things are trending toward the under in this matchup. Iowa State’s defense combined with South Dakota State hitting the under in five straight contests are two key factors to consider.

Bet online the under in this NCAA tournament game.



South Dakota State vs Iowa State ATS Pick: South Dakota State +16 ½

South Dakota State has some experience playing against Big 12 squads as the Jackrabbits started the season against Kansas State and UCF. There are no signs Iowa State should be on upset alert in this matchup.

However, there could be a bit of a letdown for the Cyclones playing a 15 seed after their thrilling run in the Big 12 tourney. Take South Dakota State to cover the 16 ½-point spread versus Iowa State at the sportsbook.



South Dakota State vs Iowa State Player Prop Pick: Charlie Easley Over 9.5 Points (-118)

Jackrabbits guard Charlie Easley just broke his streak of 10 straight games with double-digit points. The sharpshooter had back-to-back, 21-point performances against fellow Big 12 opponents Kansas State and UCF in November.



Look for Easley to overcome the Iowa State defense to go over his points prop in the March Madness betting.


South Dakota State vs Iowa State Prediction

Iowa State 72, South Dakota State 62



Questions Of The Day


What is a good March Madness prop bet to make for Thursday, March 21?

Take the over on South Dakota State guard Charlie Easley’s points prop versus Iowa State.

What are Iowa State’s odds to win the national championship?

Iowa State is tied for seventh in the NCAA tournament championship odds at +1800.


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