Michigan vs Villanova Game Preview, Live Stream, Odds, Picks & Predictions
No. 11 Seed Looks to Take Down No. 2
Villanova Seeking Eighth Straight
The Villanova Wildcats are on a tear after winning seven on the bounce, but standing in their way are the tough Michigan Wolverines.
NCAAB odds have the Wildcats at -5, so a close game is expected at AT&T Center in San Antonio, Texas.

Let’s check the latest news, stats, injury reports, and March Madness Odds for Michigan vs Villanova. We’ve plenty of predictions for you to consider.
Upset Danger with Michigan
The Michigan Wolverines have come alive at the right time and they’re a big danger to the Villanova Wildcats.
Their national championship odds are shortening with March Madness betting markets, which isn’t surprising after wins over Colorado State and Tennessee.
The Wolverines were +6½ underdogs against Tennessee, who had been well-favored to win the overall title. It was a statement 76-68 win and it should put them firmly in the tournament winner picture.
A key to the success has been center Hunter Dickinson, who led Michigan with 27 points and 11 rebounds in the Round of 32.
“Making it to the Sweet 16 is, as literal as it is, sweet because nobody believed in us,” Dickinson told ESPN. “Everybody thought we shouldn’t be in the tournament and now people that were hating on us are going home and about to watch us next week.”
The Wolverines don’t have an impressive against the spread record, but they have won three of their last four, so they’re heading in the right direction.
Villanova Cruising
As much as the Michigan Wolverines have hit form at the right time, the same applies to the Villanova Wildcats.
They’re shooting for their eighth consecutive victory and the perennial title contenders are strutting their stuff once again.
The sportsbook is starting to take notice of the Wildcats, who scored an 80-60 victory over the Delaware Blue Hens, which was followed by a gritty 71-61 victory over the Ohio State Buckeyes.
The Wildcats have covered the spread in three of their last four games and they’re 8-1 on neutral courts, so that’s a huge asset coming into the Sweet 16.
Villanova has no problem playing away from home and that’s why it’s -5-point favorites. We don’t see much between the Wildcats and Wolverines on paper, but the Wildcats’ experience in winning big games on the road could give them the edge.
They could also exploit the poor Michigan defense, which ranks 205th in points allowed, 262nd in field goal percentage and 128th in 3-point percentage.
Michigan vs Villanova Head-to-Head
The most recent meeting between the Michigan Wolverines and Villanova Wildcats came in 2018, when Michigan won 73-46 as +6½ underdogs.
It was only a regular-season contest and it was the first time in the last three meetings that it went the way of the Wolverines.
Michigan vs Villanova Game Information
- Game: Michigan Wolverines (19-14) at Villanova Wildcats (28-7)
- Location: AT&T Center, San Antonio, Texas
- Day/Time: Thursday, 7:20 p.m. ET
- Television: TBS.com
- 2022 March Madness bracket
Michigan vs Villanova Betting Lines
Michigan vs Villanova Prediction
We respect the talent of the Michigan Wolverines, but we don’t think +5 points is enough against the Villanova Wildcats.
Had NCAA basketball odds had the Wolverines at +6½, we might have entertained their chances, but as it stands, we’re in the camp of the Wildcats.
They’re riding a hot streak and they have experience winning big games at the Sweet 16 level. Michigan might have reached its ceiling, but the skies are the limit for the Wildcats.
Bookmakers have the total at 135 and we see it going over. They are high-scoring teams and we’re predicting a 77-70 game, which will see the over cash with ease.
Pick: Villanova Wildcats +5
Here’s your chance to win $1,000,000. Shoot your shot in the BetUS March Mayhem Bracket Contest.
