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NCAAB Predictions: Gonzaga, Creighton Live Dogs in Midwest

No. 1 Purdue remains the favorite in the March Madness odds to advance to the Final Four. The Boilermakers top the latest Midwest Region odds at +125.

Tennessee is next in line as the 2-seed at +225 and then there is a gap. No. 3 Creighton has +450 odds followed by No. 5 Gonzaga at +475.

NCAAB Predictions: Gonzaga, Creighton Live Dogs in Midwest
Zach Edey #15 of the Purdue Boilermakers-Andy Lyons/Getty Images/AFP

Let’s take a look at our college basketball predictions for the Sweet 16 matchups in the Midwest Region.


Gonzaga Gets Chance for Revenge vs Purdue

Purdue is a sizable 5 ½-point favorite versus Gonzaga. The over-under is set at 154½ points in the NCAA basketball odds.

Both of these teams have played as well as any squad in the NCAAB Tournament but only one can advance. This is a rematch of a Nov. 20 matchup where the Boilermakers came away with a 73-63 victory over the Zags.

Gonzaga had a 5five-point lead at the half before Purdue made a run with 43 second-half points. No player topped 15 points for Gonzaga in the previous matchup. Purdue big man Zach Edey was able to shine with 25 points and 14 rebounds.

Edey has had a dominant start to the NCAAB Tournament. The Boilermakers star is averaging 26.5 points, 17.5 boards and 3.0 blocks in the team’s first two March Madness matchups.

Gonzaga is coming off an impressive 21-point win over No. 4-seeded Kansas. The Bulldogs’ offense was a problem for the Jayhawks with plenty of ball movement and screens that led to 89 points.

Gonzaga had four players topping 15 points in this matchup. The Zags won both of their NCAA Tournament matchups by more than 20 points.

Purdue is 19-15-1 against the spread this season while Gonzaga is 17-16 ATS. The Boilermakers have gone over 23 times while the under hit 12 games. Gonzaga has hit the over in 17 matchups and 16 games have gone under.



Creighton vs Tennessee Looks to Be a Coin Flip

Tennessee is just a 2 ½-point favorite versus Creighton in the NCAAB odds. The over-under is set at 143½ points.

Vols star Dalton Knecht is one of the best guards in college basketball. Knecht is coming off a challenging outing from long range, making just 12.5% of his threes versus Texas.

The Tennessee standout is still putting up numbers in the NCAAB Tournament, averaging 20.5 points and 8.5 rebounds.

Creighton needed double overtime to survive against a red-hot Oregon squad. The Bluejays struggled early from long range but were able to hit enough shots late to advance.

Both teams are just above .500 in the Las Vegas odds this season. Creighton is a respectable 19-15 against the spread. Tennessee is 17-16-1 ATS.



Sweet 16 Predictions: Underdogs Advance to the Elite Eight

This has been an NCAA Tournament defined by favorites, but the Midwest Region is where things could get slightly turned upside down. Let’s start with why Purdue should be on upset alert.

Yes, the Zags lost the earlier matchup, but this is a much different team. Gonzaga’s performance versus Kansas may be the best any squad has looked in the NCAA Tournament.

The Bulldogs have the big guys to throw at Edey. Even if Edey gets his points in the Sweet 16, Gonzaga now has the offense to keep pace with Purdue. Coach Mark Few also has the experience of plenty of deep March Madness runs.

Tennessee is a concern if Knecht is once again struggling from long range. Creighton can be lethal from long range and was able to survive a subpar outing versus Oregon. The Vols may not be as lucky in this Sweet 16 matchup.

Give me both of the underdogs to not only cover the spread at the sportsbook but advance. Gonzaga and Creighton will square off in the Elite Eight with a trip to the Final Four on the line.


Questions Of The Day

What are Gonzaga’s odds to make the Final Four?

Gonzaga is last in the Midwest Region for the Final Four odds at +475.

Where is Purdue center Zach Edey projected to go in the 2024 NBA draft?

Zach Edey is projected to be a top-15 pick in the NBA draft.

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