Arizona vs Duke Same Game Parlay Picks for March Madness 2025 Sweet 16 Round

Arizona was favored against Duke when the teams met in the regular season. That is not the case in Thursday’s East Regional semifinal at the Prudential Center in Newark, N.J..

Duke barely broke a sweat in its first two March Madness games while Arizona was fortunate to get by former Pac-12 rival Oregon to reach the Sweet 16. Now the teams meet in the NCAA Tournament for the first time since 2011.

The last time Arizona and Duke played in the Sweet 16 👀🍿 pic.twitter.com/aSqNY3FGpZ

— Justin Spears (@JustinESports) March 24, 2025

The NCAA basketball odds list Duke as the 9-point favorite with -550 odds to win outright. Arizona is priced at +425 to reach the Elite Eight for the first time since 2015.

Arizona vs Duke Free Sweet 16 Parlay Picks Today, March 27

• Duke ATS Pick -9

Four of Arizona’s losses this season have come by 14 points or more, so when things go south for the Wildcats, it isn’t always pretty.

I prefer to see the March Madness line in the 7-8 range and perhaps that will happen before the opening tip.

Even if it stays at 9, take Duke to pull away late and cover when looking at the March Madness best picks.

Bet on Duke ATS -9

• Arizona vs Duke Over/Under Pick

Duke has scored 89 and 93 in its first two NCAA Tournament games while Arizona put up 93 and 87 points while allowing an average of 78 points, so the NCAAB expert picks won’t be projecting a defensive slugfest.

The March Madness betting line total of 153.5 is the third highest among Thursday’s four March Madness games. Even though the teams combined for just 124 points in the regular-season meeting, go with the game to finish over 153.5 when considering March Madness best bets.

Bet Arizona vs Duke game over 153.5

• Player Prop Pick: Cooper Flagg

Cooper Flagg has played less than 30 minutes in each of the first two NCAA Tournament games, per Arizona vs Duke stats. He still averaged 16 points, 8.0 rebounds and 5.5 assists in the two victories.

SWEET DUB 🍭🍬👿 pic.twitter.com/Pp7FFOySN4

— Duke Men’s Basketball (@DukeMBB) March 23, 2025

Take a look at the -106 odds for Flagg to have at least 35 combined points, rebounds and assists in this NCAA basketball game.

Bet Cooper Flagg to have 35+ Points, Rebounds and Assists (-106)

• Game Prop Pick: Duke to Reach 10+ Pts 1st

Arizona trailed Oregon 10-4 in the early going before turning things around. While the Wildcats would be smart to come out firing, I’ll go with the -176 odds for Duke to hit the 10-point mark before Arizona.

Bet Duke to Reach 10+ Points First (-176)

Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets.

Arizona vs Duke How To Watch

• Game: Arizona (24-12) vs Duke (33-3)
• Date/Time: Thursday, March 27, 9:39 p.m. ET
• Location: Prudential Center, Newark, NJ
• Arizona vs Duke Live Stream: Fubo.tv

Check here for Arizona vs Duke betting tips.

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