Arizona vs Houston Prediction, Odds and College Basketball Picks: Back Wildcats ATS +6 In Big 12 Tourney Final on March 15

Things didn’t go so well when Houston played in the 2024 Big 12 tournament championship game, with the Cougars managing just 41 points in a 28-point loss to Iowa State. Will history repeat when Houston clashes with Arizona with a Big 12 tournament title on the line on Saturday?

Houston (+700) is tied for third in the odds to win March Madness odds. Arizona is tied for 13th at +5000 in the championship odds.

The last time that the Wildcats and Cougars met in March came in the 2022 NCAA Tournament with Arizona still playing in the Pac-12 and Houston a member of the American Athletic Conference.

Arizona has covered against the spread in just four of its eight games as the underdog this season, while Houston is 16-16 ATS when listed by BetUS Sportsbook as the favorite.

Houston covered as a 2.5-point favorite in the lone meeting between these schools in the regular season. The Cougars are six-point favorites for Saturday’s rematch, with the over/under set at 135 points.

Arizona vs Houston Prediction Today

There isn’t much history between the Wildcats and the Cougars, who hadn’t met in the regular season in 16 years before Houston’s 62-58 victory in mid-February.

Houston can make college basketball news with a win, as it would lock up a No. 1 seed in the March Madness bracket. Go with the Cougars to add the tournament title to their Big 12 regular-season championship when making your picks. Score prediction: Houston 68, Arizona 65.

See what@CoachSampsonUH,@emanuelsharp_&@LjCryersaid after tonight’s Phillips 66@Big12ConferenceChampionship Semifinal win over #17/18 (4) BYU

NEXT – vs rv/#24 Arizona, Phillips 66 Big 12 Championship Title Game, 5 pm Saturday, Kansas City, Mo.https://t.co/9DpD0AtwdC

— Houston Men’s Hoops 🏀 🐾 (@UHCougarMBK)March 15, 2025

Arizona vs Houston How to Watch

• Game: Arizona (22-11) vs Houston (29-4)
• Date/Time: Saturday, March 15, 6:00 p.m. ET
• Location: T-Mobile Arena, Kansas City, MO
• Arizona vs Houston Live Stream: TBS.com

Find Arizona vs Houston betting trends here.

Top 2 Arizona vs Houston Betting Picks

1. Arizona ATS +6.5

Houston had failed to deliver against the NCAAB basketball lines in its previous four games before cruising to a 20-point win in the Big 12 tournament semifinals against BYU. Expect things to be a little more challenging in this contest.

The Wildcats are 6-3 outright against ranked teams since the start of December, with two of the losses by four points or less.

CATS TO THE CHAMPIONSHIP ‼️@ArizonaMBB is headed to its first-ever Phillips 66 Big 12 Men’s Basketball Championship Final.

No. 3-seed Arizona takes on No. 1-seed Houston for all the marbles tomorrow at 6 p.m. ET.#Big12MBB | @Phillips66Gas pic.twitter.com/uBiG71nnbF

— Big 12 Conference (@Big12Conference) March 15, 2025

Caleb Love’s 27 points led Arizona past Texas Tech in the semifinals. This is not his first rodeo, so keep that in mind when making Arizona vs Houston best bets. Go with Arizona to cover as the six-point underdog.

Bet On Arizona +6 vs Houston

2. Arizona vs Houston Under 135

This is the bet where I would tread carefully. Houston is an elite defensive team, with five of the last seven games played by the Cougars landing under the college basketball odds total. Meanwhile, Arizona has averaged 87 points over its last seven games.

Per the Arizona vs Houston stats, the Wildcats were held under 60 points four times this season, and one of those came at home against Houston. Go with the Big 12 title game to land under 135 points when making your college basketball bets.

Bet On Arizona vs Houston Under 135

Arizona vs Houston Best Player Prop Bet

• Houston G L.J. Cryer Over 16.5 Points (-115)

Houston guard L.J. Cryer has scored at least 20 points in four of his last five games and has 16 3-pointers over his last four games.

Despite not attempting a free throw, he had 15 points in the last meeting with Arizona.

When looking at the college basketball player prop options, take Cryer at -115 to go over 16.5 points.

Bet on L.J. Cryer Over 16.5 Points

Question of the Day

Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets.