College Basketball Odds and Picks: Bet Creighton To Win December 18
- Get the latest college basketball odds at the BetUS Sportsbook.
- Creighton is a best bet as a road favorite against Georgetown.
- Go with the Oklahoma-Michigan game to land under.
- Find my top college basketball betting picks ahead.
Eight of the nine ranked teams in action came away with wins on Tuesday with six of them covering against the college basketball spread. Will that betting trend continue with eight more teams hitting the court on Wednesday? The only matchup between ranked teams will come when No. 14 Oklahoma is a 3-point underdog against No. 24 Michigan in the Jumpman Invitational.

Here are my top NCAAB expert picks to bet on today.
Top 3 College Basketball Picks Today
1. Creighton (-162) At Georgetown
Creighton certainly misses the Texas Tech transfer and its No. 2 scorer Pop Isaacs as he will be sidelined for the rest of the season with a hip injury. However, seeing the Bluejays only favored by 3½ points on the road against Georgetown is sure to generate plenty of action among those who bet online.
The Bluejays’ four losses have come against ranked Texas A&M and Alabama teams, Nebraska out of the Big Ten, and a perennial NCAA tournament team in San Diego State. With the inside-outside duo of Ryan Kalkbrenner and Steven Ashworth, this Creighton team is still one of the top teams in the Big East.
Steven Ashworth found Ryan Kalkbrenner for the @MentorTeamMates Highlight of the Game 🙌#GoJays pic.twitter.com/7bMDAiRlpK
— Creighton Men’s Basketball (@BluejayMBB) December 17, 2024
Georgetown bounced back from a double-digit loss to West Virginia by winning on the road against former conference rival Syracuse.
Creighton has won six games in a row against Georgetown and covered in the last three. Ed Cooley hit the transfer portal to improve Georgetown after a difficult first season with the Hoyas. This is a game where it can provide answers whether Georgetown will be a factor in the Big East race.
One of the top options in the Dec. 18 college basketball picks is Creighton at -162 to win in its Big East opener.
Bet: Creighton (-162) vs Georgetown
2. Oklahoma vs Michigan to Go Under 150.5
The only game on Wednesday between ranked teams comes in Charlotte, North Carolina when undefeated Oklahoma faces a Michigan team coming off a two-point loss to Arkansas.
Matchup against Michigan 🥊@Jumpman23 x #BoomerSooner ☝️ pic.twitter.com/UGzcBKvmSh
— Oklahoma Basketball (@OU_MBBall) December 17, 2024
The last time Michigan faced a ranked team, the Wolverines finished with just 67 points on 39% shooting in a win over Wisconsin.
When looking at college basketball betting trends, Oklahoma averages 76.8 points in four games against teams from the Power-4 conferences and nearly 85 points in the other six games. That is enough to go with the game to land under the 150.5-point total set by the sports betting odds.
Bet on Michigan vs Oklahoma Under 150.5
3. Xavier vs UConn Over 146.5
Seven of the last nine times that Xavier squared off with UConn, the game landed over the total. The Huskies put up 80 and 99 points in the two regular-season games against the Musketeers last season.
Xavier is 60th in the Pomeroy basketball database in defensive efficiency while UConn ranks 70th. The Huskies will be without Samson Johnson, their best interior defender as he is in concussion protocol. That could open up room for Zach Freemantle to operate in the lane. He could be an option in the college basketball player prop bets.
There are some who might like Xavier to cover as the 13½-point underdog. When looking at college basketball betting lines today, we’ll take the game to land over the 146½-point total,
Bet on Xavier-UConn to land over 146.5 points
Questions of the Day
Which college basketball team is the heaviest favorite at BetUS on Wednesday?
Houston is favored by 29 points against Toledo.
What college basketball game has the highest total at BetUS on Wednesday?
The Samford-Arizona game has a total of 168 points.
Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets.