Kentucky vs Missouri Prediction, Game Preview, Live Stream, Odds and Picks
Wildcats Face Host Tigers in SEC Showdown
Tigers on Two-Game Win Streak
The Missouri Tigers look for their third straight victory when they host the No. 19 Kentucky Wildcats in the SEC opener for both teams on Wednesday night. Missouri is coming off a rout of Illinois on Thursday and has just one loss on the season heading into conference play. Kentucky routed Florida A&M at home on Dec. 21 in its last contest, bouncing back from a loss to UCLA. Both teams want to get off to a quick start in league play, so look for a tight battle throughout. To help with your betting online, check out our in-depth preview of this contest.
Let’s check the latest college basketball odds, stats, injury reports and college basketball lines for Kentucky vs Missouri. We’ve plenty of NCAA basketball odds for you to consider.

Kentucky Shows Potential in Blowout
The Kentucky Wildcats have had their troubles in the early going of the season, but they are still one of the most talented teams in the SEC and are hoping things come together against conference competition. The team showed how good it can be with a 20-point win over Florida A&M in its last game, shooting 56.5% from 3-point range and making a season-high 13 shots from beyond the arc.
Freshman Cason Wallace had a career-high 27 points along with nine assists and four steals. The 6-4 guard is averaging 11.8 points, 4.4 assists, and 2.5 steals this season, causing problems for opponents on both ends of the floor.
Reigning national player of the year, Oscar Tshiebwe, is second in the country in rebounding with 13.0 per game. He’s also scoring a team-high 15.0 points per game, shooting 56.4% from the floor.
After transferring from Illinois State, Guard Antonio Reeves has been an offensive spark for the Wildcats in his first season with the team. Reeves is scoring 12.8 points per game, shooting 43.7% from 3-point range.
Brown Leads Missouri in Easy Win Over Illinois
The Missouri Tigers had a game to remember just before the Christmas break, blowing out No. 16 Illinois by 22 points in the annual rivalry game on Thursday, led by senior Kobe Brown. The guard had career highs with 31 points and eight assists, earning SEC Player of the Week honors for the performance.
“I approached it like every other game,” Brown said after Thursday’s victory. “I just wanted to come out and win, to just come out on top as a team. The ball went in for me tonight, so I’m happy about that, but I just want to win.”
Brown is averaging 14.4 points, 5.7 rebounds, and 1.3 steals per game this season. He had scored in single digits in the two contests before the Illinois game.
Senior guard D’Moi Hodge is pacing the Tigers in scoring with 16.7 points per game, averaging 4.1 rebounds and 2.8 steals per contest. Hodge had 20 points and four steals in the win over Illinois.
Kentucky vs Missouri Game Injuries
Kentucky vs Missouri Head-to-Head
The Kentucky Wildcats have dominated their rivalry with the Missouri Tigers, taking 12 of the first 14 matchups. However, Missouri’s only wins in the rivalry have come in the last six meetings.
Missouri’s last victory came at home in February 2021, and the Tigers are 2-6 at home against the Wildcats. The college basketball lines for Wednesday’s game give the visiting Wildcats the slight edge to come away with the victory.
Kentucky vs Missouri Game Information
- Game: (No.19) Kentucky (8-3, 0-0 SEC) vs Missouri (11-1, 0-0)
- Location: Mizzou Arena, Columbia, MO
- Day/Time: Wednesday, Dec. 28, 7:00 p.m. ET
- Kentucky vs Missouri Live stream: TBS.com
Kentucky vs Missouri Betting Lines
Kentucky vs Missouri Picks & Prediction
The Missouri Tigers were able to overwhelm Illinois with their defense in last week’s win, but the Kentucky Wildcats should be ready for that. This will be a tight contest, but we like the Wildcats to pull away for the win.
When making your college basketball picks, take Kentucky to win and cover on the road.
Kentucky is listed at -150 in our Vegas lines. This means that if you wager $100 on Kentucky, you have a chance to win $67. Missouri is +130, offering a chance to win $100 on a $130 wager.
The implied probability attached to the betting lines gives Kentucky a 60.00% chance to win, with Missouri at 43.48%.