Lipscomb vs Iowa State Odds, Prediction and March Madness Picks March 21

March Madness betting is back, and with it comes a first-round matchup between Lipscomb and Iowa State. The Bisons aren’t exactly a tournament regular, while the Cyclones are looking to make a deep run.

The college basketball odds heavily favor Iowa State, but Lipscomb has the firepower to keep things interesting. Before locking in your bets, let’s break this matchup down.

Lipscomb vs Iowa State Prediction Today, March 21

My prediction

This one’s set to be a shootout, with both teams averaging over 79 points per game. Lipscomb’s shooting 47.3% from the field, while Iowa State sits just ahead at 48%. While the NCAA championship basketball odds favor the Cyclones, it’s  Lipscomb’s perimeter defense (holding opponents to 30.8% from deep) that will be the game-decider here. Bisons cover.

Top 3 Lipscomb vs Iowa State Betting Picks

My top picks

• Lipscomb vs Iowa State ATS Pick: Lipscomb +14.5
• Lipscomb vs Iowa State O/U Pick: Under 143
• Lipscomb vs Iowa State best point-scorer bet: Joe Anderson 3+ threes (+114)

My Analysis

No doubt, the Bisons have their work cut out against a potent Cyclones offense. And while Lipscomb’s offense is just as efficient, their perimeter defense will be the difference-maker, slowing Iowa State just enough to keep this one tight. My March Madness predictions have Iowa State taking it outright, but Lipscomb covers.

Even though I expect Lipscomb’s defense to ramp up the pressure on the perimeter, the truth is, both teams are too efficient offensively not to put up points this game. I’m going against the NCAA basketball news here – this one is soaring past the over mark with ease.

With Lipscomb leading scorer Jacob Ognacevich drawing most of the Cyclones’ defensive attention, this sets up Bison sharpshooter Joe Anderson to shine. Anderson has drilled 4+ threes in three straight and remains Lipscomb’s go-to sniper. I’m locking him in to step up in these March Madness games and drain 3+ triples again.

Lipscomb vs Iowa State March Madness Best Prop Bet

• Jacob Ognacevic Under 7.5 Rebounds (-145)

Look, no questions asked, you can count on Lipscomb’s top scorer, Ognacevich, to get his points. But don’t expect much on the rebounding front. Going up against a Cyclones team that is giving up just 31.8 boards per game (38th in the nation), they’ll make sure he doesn’t crash the glass. Will he grab a few loose rebounds? Sure. More than seven? No chance.

Bet on Jacob Ognacevic Under 7.5 rebounds

Lipscomb vs Iowa State How to Watch

• Game: Lipscomb Bisons (26-7) vs. Iowa State Cyclones (23-10)
• Location: Fiserv Forum, Milwaukee, WI
• Date/Time: Mar. 21, 1:30 p.m. ET
• Lipscomb vs Iowa State Live Stream: FuboTV

Get the latest Lipscomb vs Iowa State betting trends here.

Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets