Marquette vs Villanova Prediction, Odds and Best Bet Today: Bet Golden Eagles to Cover As Road Favorite February 21
- Look for the Marquette vs Villanova game to land over 142.5 points.
- Take Marquette to cover as a -2 road favorite versus Villanova.
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Marquette vs Villanova College Basketball Best Bets


Place your Bets on Marquette vs Villanova at BetUS Sportsbook!

Marquette is the road favorite against Villanova for the first time since 2012 as the Golden Eagles look to sweep the season series and extend their winning streak against Villanova to nine games.
Villanova looks to improve to 4-1 against ranked teams this season. The Wildcats are very much a bubble team as they are tied for 41st at +25000 in the odds of winning March Madness. With just one Quad 1 this season, this is a huge game for Villanova.
Since dropping back-to-back games to St. John’s and Creighton, Marquette returned to its winning ways after defeating cellar-dwelling DePaul and Seton Hall teams. Winning at Villanova will be a little more challenging as the Wildcats are 2-0 both outright and against the college basketball spread as a home underdog this season.
MKE ➡️ PHILLY @continentaltire | #MUBB pic.twitter.com/Dq0pAzZh0k
— Marquette Basketball (@MarquetteMBB) February 20, 2025
Marquette has won all five of its games as the road favorite but has covered in just three of them.
Marquette vs Villanova Prediction Today
The last time Villanova played at home, the Wildcats handed St. John’s its first conference loss of the season. They also beat two-time defending national champion UConn at home and nearly took down Creighton as well.
We like Marquette to avoid a similar fate and cover when listed by the BetUS sportsbook as a 2-point favorite. Score prediction: Marquette 74, Villanova 70.
Marquette vs Villanova How To Watch
- Game: Marquette (20-6, 11-4 Big East) vs Villanova (15-12, 8-8)
- Date/Time: Friday, Feb. 21, 7 p.m. ET
- Location: Finneran Pavilion, Villanova, Pa.
- Marquette vs Villanova Live Stream: Fubo.Tv
Find Marquette vs Villanova betting trends here.
Top 2 Marquette vs Villanova Betting Picks
1. Marquette vs Villanova ATS Pick: Marquette
Marquette has covered in each of its last three games at Villanova and when the team met earlier this season in Milwaukee it wasn’t much of a game with the Golden Eagles soaring to the 13-point win.
Spoke to #Villanova Coach Kyle Neptune following Practice for Tomorrow game vs 16th Ranked #Marquette at Wells Fargo Center #NovaNation pic.twitter.com/vnwmE6ueHW
— David Malandra Jr (@DaveMReports) February 20, 2025
Expect a closer game on Friday, but take Marquette to cover at -2 (-110).
2. Marquette vs Villanova O/U Pick: Over
Three of the last four games between Marquette and Villanova finished over the sports betting odds total. When the teams met less than a month ago, the game went over the 142-point total with 2:10 left to play.
Bet on Marquette vs Villanova Over 142.5.
Marquette vs Villanova Best Player Prop Bet
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Kam Jones Over 18.5 points (-106)
In his last three games after scoring 14 points or fewer, Marquette’s Kam Jones is averaging 23 points, seven assists and 3.7 rebounds. He scored 14 in his last game. Jones went off for 27 points and six assists against Creighton in his most recent road game, so take Jones to go over 18.5 points (-106).
More College Basketball Picks and Best Bets For February 21
Questions of the Day
What are Villanova and Marquette’s records against the spread?
Villanova is 14-13 and Marquette is 12-13-1 against the spread this season.
Who were the leading scorers the last time Villanova faced Marquette?
Stevie Mitchell had 21 points to lead Marquette to its 87-74 victory on Jan. 24. Jordan Longino had 27 points for Villanova.
Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets.