Mississippi State vs Alabama Prediction, Odds and Best Bet Today Feb 25

The only game on Tuesday between two teams in the top 25 in The Associated Press Division I men’s basketball poll takes place in Tuscaloosa as No. 6 Alabama welcomes 24th-ranked Mississippi State to town. Are the Bulldogs a sure thing to make it into the March Madness bracket or a bubble team? A win on Tuesday would help keep the bubble from bursting for Mississippi State.

Alabama is sixth at +1200 in the odds of winning March Madness. Mississippi State comes in at +10000 in the championship odds.

Mississippi State vs Alabama Prediction Today

Alabama rebounded from allowing 110 points in a road loss to Missouri by beating Kentucky behind 30 points from Mark Sears. Mississippi State is 5-6 against ranked teams this season but when facing top-10 teams on the road, the Bulldogs lost to Tennessee by 12 points and fell to Auburn by 22, per NCAAB betting trends.

The final three games of the regular season for Alabama come against top-10 teams so this is a matchup where the Crimson Tide needs to take care of business.

Go with Alabama to pick up its 12th home win of the season when making Feb. 25 college basketball picks, Score prediction: Alabama 92, Mississippi State 80.

Mississippi State vs Alabama How to Watch

• Game: Mississippi State (19-8, 7-7 SEC) vs Alabama (22-5, 11-3)
• Date/Time: Tuesday, Feb. 25, 9 p.m. ET
• Location: Coleman Coliseum, Tuscaloosa, AL
• Mississippi State vs Alabama Live Stream: Fubo.TV

Find Mississippi State vs Alabama stats here.

Top 3 Mississippi State vs Alabama Betting Picks

1. Mississippi State vs Alabama ATS Pick

Alabama has won seven straight games against Mississippi State and covered against the college basketball spread in the last four.

Tuesday Night Lights ✨ 🤩

🆚 Mississippi State
📍 Coleman Coliseum
⏰ 8 PM #RollTide | @AlabamaMBB pic.twitter.com/DamisyEhL8

— Alabama Athletics (@UA_Athletics) February 25, 2025

The last time that Mississippi State played in Tuscaloosa, the Crimson Tide had no trouble proving that the Bulldogs had more bark than bite in a 32-point win. Expect a more competitive showing this time

Go with Alabama to cover as the 8-point favorite when looking at the Mississippi State vs Alabama best bets.

Bet on Alabama (-8)

2. Mississippi State vs Alabama O/U 171.5

Six of the last eight times that the Bulldogs squared off with the Crimson Tide, the game landed over the sports betting odds total.

Even though just four of Alabama’s first 13 home games landed over the total, when making Feb. 25 college basketball bets, take the game to go over 171.5.

Bet this Pick: Over 171.5

3. First Half Over 81 (-115)

There have been mixed results for Alabama when listed by the BetUS sportsbook as the home favorite with a 7-6 mark against the spread while Mississippi State is 2-2 outright and against the spread as the road underdog. Bet first-half scoring line to go over 81 points.

Bet This Pick: First Half Over 81 Points (-115)

Mississippi State vs Alabama Best Player Prop Bet

• Mark Sears To Have 31+ Points, Rebounds, Assists (+117)

It is safe to say that Alabama’s All-American guard Mark Sears is rolling these days with 35 and 30 points in his last two games. He flirted with a triple-double in the first meeting with Mississippi State this season before finishing with 17 points, six rebounds and nine assists.

🏀 SEC Player of the Week: Feb. 24

🐘 Mark Sears@AlabamaMBB x #SECMBB pic.twitter.com/I6Avu11YnB

— Southeastern Conference (@SEC) February 25, 2025

Sears at +117 to have at least 31 combined points, rebounds and assists is a college basketball player prop bet to consider.

Bet on Mark Sears To Have 31+ Points, Rebounds, Assists (+117)

More College Basketball Picks and Best Bets For February 25

• Duke vs Miami Prediction, Odds and Best Bet Today
• College Basketball Predictions and Odds Today: Best Bet Florida ATS vs Georgia
• Tennessee vs LSU Prediction, Odds and Best Bet Today: Vols (-10½) Top Pick

Questions of the Day

Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets