NCAAB Picks and Predictions: NC State ATS vs Duke is Best Bet on January 27
- Duke may struggle to cover as a huge home favorite against NC State
- Bet on Iowa State vs Arizona game to land over 152
- Make bank with our top NCAAB picks! Join with our promo code HUDDLE125.
With eight ranked teams losing over the weekend, it is clear that March Madness isn’t too far away from arriving. Duke and Iowa State, two of the top title contenders, lead the list of teams hitting the court on Monday.

When looking at the NCAA basketball futures odds, Duke (+700) is second behind only Auburn in the odds of winning March Madness. Iowa State is tied for fourth at +1200 in the championship odds.
Let’s take a look at some options from Monday’s college basketball schedule.
Top 3 NCAAB Prop Picks Today
1. North Carolina State ATS at Duke
Duke is rolling right along as the Blue Devils are the only team that is still perfect in ACC play this season. Duke also leads the ACC with a 12-7 mark against the college basketball spread.
The Wolfpack won the last two games against Duke. The last time the teams met, it was North Carolina State coming up with the upset with a spot in the Final Four of the 2024 March Madness bracket on the line. NC State also knocked Duke out of the ACC tournament.
back in Cameron Monday night‼️
⏰ 8:30 PM ET
🆚 NC State
📺 ESPN pic.twitter.com/HGz9ApVEyr— Duke Men’s Basketball (@DukeMBB) January 26, 2025
This is a much different Duke team with freshmen Cooper Flagg and Kon Knueppel helping the Blue Devils win 13 games in a row and post a gaudy 11-0 record at home, per NC State vs Duke stats.
NC State is limping along with a 2-6 ACC record and it doesn’t look good for the Wolfpack to pick up their first road win of the season or snap a four-game losing streak.
When making NCAAB picks, keep in mind that Duke hasn’t been favored by at least 20 points against North Carolina State since 2009. The Blue Devils won that game outright but failed to cover. Don’t be surprised if history repeats on Monday.
Bet On North Carolina State +21 (-115)
2. Iowa State vs Arizona Over 152 (-110)
Iowa State’s lone Big 12 loss came on the road against West Virginia. While it is no easy task winning in Morgantown, hitting the road to face Arizona is no walk in the park either.
The last time that Iowa State faced Arizona in Tucson was in 1990, so the head-to-head results will not be of much use for those looking at college basketball betting trends.
Tomorrow’s game vs Iowa State is officially 𝙎𝙊𝙇𝘿 𝙊𝙐𝙏 🐻⬇️ pic.twitter.com/foO1OQmwem
— Arizona Basketball (@ArizonaMBB) January 26, 2025
This feels like a game that could go either way as the winner of this game will close within a half-game of first-place Houston in the Big 12 standings.
Our college basketball odds list Arizona as a 2½-point favorite with -145 odds to win the game outright. It might be a better option to look at the 152-point total.
Both teams rank in the top 30 in both offensive and defensive efficiency per the Pomeroy basketball ratings. Iowa State is less than a week removed from scoring 108 in a win over UCF. Don’t expect that much offense but when looking at Iowa State vs Arizona best bets, take the game to over 152.
Bet Iowa State vs Arizona Game Over 152 (-110)
3. UCLA (-115) to Win at USC
Maybe facing a familiar foe is just what a slumping UCLA team needs to get back to playing winning basketball as the BetUS sportsbook has the Bruins as a slight road favorite against rival USC.
UCLA won four of the previous five games against the Trojans before USC’s 62-56 win on the road to earn a split of the regular-season series during the 2023-24 season.
It has been a bit of an adjustment as both teams are in the middle of the pack of their first season in the Big Ten. The Bruins are just 2-3 on the road, although they did win at Washington in its most recent game away from home, per UCLA vs USC betting tips.
Washington is the only Big Ten team with more home losses this season than USC.
The Trojans have been without senior forward Terrance Williams since a Dec. 4 loss to Oregon while UCLA should have all of its top players for this game. That is enough to bet online on UCLA at -110 to win outright.
Questions Of The Day
Which college basketball team is the heaviest favorite at BetUS Sportsbook on Monday?
Duke is favored by 215 against North Carolina State while Southern is a 21.5-point favorite against Mississippi Valley State. .
Which game has the highest total on Monday?
The Penn State vs Michigan game has a total of 160 points. .
Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets