The Week 10 schedule in the Pac-12 is all about the top teams staying in contention for the conference title game.
Oregon, UCLA, USC, and defending champion Utah are all favored by more than 10 points, so a stumble this week could seriously damage their conference championship hopes.
Oregon (even-money) has the best odds to win the Pac-12 title, according to the sportsbook, followed by USC at +250. Utah and UCLA are priced at +425.
Oregon remains at No. 8, USC is ranked ninth in both national polls, UCLA is 10th in the Associated Press poll and 11th in the American Football Coaches Association ranking, while Utah comes in at No. 12 in both polls.
According to the college football playoff odds, the Ducks come in at +4000 in the odds to win the national title, USC next at +6000.
Let’s check the latest NCAAF picks, stats, injury reports and NCAAF predictions. We’ve plenty of NCAAF expert picks for you to consider.
Game of the Week
Oregon State Beavers vs Washington Huskies
- Date, time (TV): Friday, Nov. 4th, 10:30 p.m. (ESPN)
- Line: Washington -3
Consider this an elimination game when it comes to the Pac-12 title game. Both teams have 6-2 overall records and are 3-2 in conference play, so the loser will be two games out of a spot in the Pac-12 title contest.
Oregon State is one of two Pac-12 teams with more interceptions than touchdown passes allowed, while Washington features Michael Penix Jr., the conference leader with 2,934 passing yards, 230 completions, and 339 passing attempts.
Washington’s Rome Odunze leads the Pac-12 with an average of 108 receiving yards per game.
Washington’s Bralen Trice and Jeremiah Martin have combined for 12½ sacks and will look to disrupt the Oregon State passing game. Washington has 25 sacks, five more than the Huskies had a season ago.
The Dawgs defense leads the Pac with 𝟐𝟓 sacks on the season 👀🔒💪#NoLimits #PurpleReign pic.twitter.com/OHOB8EswmL
— Washington Football (@UW_Football) October 28, 2022
Oregon State’s Jaydon Grant and Ryan Cooper Jr. each have three interceptions.
The Beavers snapped a nine-game losing streak to Washington with last year’s 27-24 win. Oregon State has covered four of the last six games against Washington.
Rest of the Schedule
Oregon Ducks vs Colorado Buffaloes
- Date, time (TV): Saturday, Nov. 5th, 3:30 p.m. (ESPN)
- Line: Oregon -31½
Oregon (7-1, 5-0 in the Pac-12) leads the conference in total offense, averaging 526 yards per game, while Colorado allows 483.8 yards, the most in the conference, so this has the potential to get ugly.
Oregon quarterback Bo Nix leads the conference with a passing rating of 169.7, completing 72.3% of his passes with 20 TD passes and five interceptions. His passing efficiency and completion percentage numbers are slightly better in conference play.
Tony Franklin and Chase Cota, Oregon’s top two receivers, are both questionable for the game.
Colorado (1-7, 1-4) allowed Arizona State to throw for 435 yards and three TDs the last time out.
Colorado has covered in two of the last three meetings, even though the Buffaloes own one win against Oregon since 2000.
Washington State Cougars vs Stanford Cardinal
- Date, time (TV): Saturday, Nov. 5th, 3:30 p.m. (ESPN)
- Line: Washington State -6 Ev
Stanford (3-5, 1-5) is allowing the second-fewest passing yards in the Pac-12, with opponents completing just 58.8% of their passes. Those numbers will be at risk with Cameron Ward leading the Washington State offense.
Although Ward has thrown the most interceptions in the conference, he has just one in 117 passing attempts over the last three games.
Washington State (4-4, 1-4) is looking to snap a three-game losing streak, and it has been the offense that has come up short, as the Cougars have allowed 41 points over those three contests.
Stanford’s offense took a hit with the recent injury to running back Casey Filkins.
Washington State has won five games in a row against Stanford and covered against the college football betting lines in the last six meetings.
Arizona Wildcats vs Utah Utes
- Date, time (TV): Saturday, Nov. 5th, 7:30 p.m. (Pac-12 Network)
- Line: Utah -17 ½
Utah quarterback Cameron Rising, one of five Pac-12 players averaging more than 300 yards of total offense per game, was a late scratch in last week’s hard-earned win over Washington State.
Keep an eye on his status, as Utah could put up some big numbers playing against an Arizona defense that is allowing opponents to complete 70.8% of their passes. Rising, leading rusher Tavion Thomas and star tight end Dalton Kincaid are questionable for the contest.
Arizona (3-5, 1-4) is second in the conference with 340.1 passing yards per game. Jacob Cowing and Dorian Singer are first and third in the Pac-12 in receiving yards.
Utah (6-2, 4-1) has won five games in a row against Arizona, with the average margin of victory being 18 points.
The Wildcats haven’t won at Utah since 2014.
UCLA Bruins vs Arizona State Sun Devils
- Date, time (TV): Saturday, Nov. 5th, 10:30 p.m. (FS1)
- Line: UCLA -11
UCLA quarterback Dorian Thompson-Robinson was limited to 199 passing yards with no touchdowns in last week’s win over Stanford. There was little reason to throw the ball, with Pac-12 rushing leader Zach Charbonnet averaging 9.4 yards per carry and rushing for 198 yards in the game.
Arizona State’s Xazavian Valladay is tied for second in the conference with 760 rushing yards.
Arizona State (3-5, 2-3) has been pretty solid against the pass, allowing 10 TD passes while intercepting nine passes.
UCLA (7-1, 4-1) has covered against the college football odds in four of the last five games in the series.


California Bears vs Southern California Trojans
- Date, time (TV): Saturday, Nov. 5th, 10:30 p.m. (ESPN)
- Line: USC -21½
Cal (3-5, 1-4) has allowed more passing yards per game than any other conference team, and now the Bears get to face USC quarterback Caleb Williams, who has 10 touchdown passes and no interceptions over the last three games.
USC’s top receiver Jordan Addison didn’t play last week so keep an eye on his status. Addison is questionable, as is leading tackler Eric Gentry.
Travis Dye has run for more than 100 yards in two of the last three games for the Trojans (7-1, 5-1), while Cal’s Jaydn Ott has rushed for 212 yards over the last four games since his 274-yard effort against Arizona.
Something to consider for those who bet online: six of the last seven games in the series went under the total.