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College Football Betting: Biggest Upset of Week 13

The college football season heads into Week 13 and there are some delicious upset scenarios to consider when you eat your Thanksgiving dinner.

Let’s look at three games in the sportsbook, which particularly jump off the page.

Sooners at Cowboys
Brian Bahr/Getty Images/AFP

UPSET OF THE WEEK

Oklahoma Sooners at Oklahoma State Cowboys
Odds: Oklahoma State -4

The upset of the week for college football picks is one that doesn’t feel like an upset if it happens. The Oklahoma Sooners have won the last six Big 12 championships.

They have regularly won this head-to-head matchup against Oklahoma State, which is called Bedlam. Lincoln Riley, the head coach at Oklahoma, has regularly outfoxed and outflanked Oklahoma State head coach Mike Gundy.

It is true that Oklahoma State has been really good this year, and also true that OSU defensive coordinator Jim Knowles has probably been the best assistant coach in the country.

He will be a likely finalist for the Broyles Award, annually given to the best assistant coach in the United States. Nevertheless, Oklahoma has a solid defense this season, far better than previous years.

The Sooners contained the Iowa State Cyclones’ offense this past weekend in a 28-21 win. The Sooners will not allow Oklahoma State’s offense to run wild. The game will be close and tense, but Oklahoma usually finds a way to make that one key play in Bedlam.

The Sooners aren’t miles better than Oklahoma State this year – unlike other years – but they will do enough to win the game in the end.

Oklahoma’s ability to win Big 12 titles and come through in huge moments is something which will serve the Sooners well in this pressure-packed environment in Stillwater, Oklahoma.

HONORABLE MENTION

Kentucky Wildcats at Louisville Cardinals
Odds: Louisville -3

The Kentucky defense is banged up, but head coach Mark Stoops has owned this rivalry in recent years.

He gets the Wildcats to play their best against Louisville in this battle for bragging rights in the Commonwealth of Kentucky. Louisville has had a decent but not great season under head coach Scott Satterfield.

The Cardinals are not a bad team, but they do seem to be getting a lot of respect here, which – much like Oklahoma State being favored over Oklahoma – cuts against the recent history of this football rivalry.

The opponent has had the upper hand on the gridiron, so a Louisville win would break with precedent. Louisville is not good enough in 2021 to justify this level of respect.

Kentucky will own the second half and get just enough defensive stops to win what will probably be a shootout. Take the over if you bet online.

Florida State Seminoles at Florida Gators
Odds: Florida -2.5

The Florida Gators just fired Dan Mullen. Meanwhile, Florida State is coming off a win at Boston College which has coach Mike Norvell confident his players will be able to continue to perform at a higher level.

Florida State started the season horribly but has made tangible improvements, whereas Florida started the season by almost upsetting Alabama and then has steadily deteriorated over the past several weeks.

Florida State is an underdog on the NCAA odds that should bark loudly. The Seminoles will win outright on the road in Gainesville.

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