Colorado vs Washington Prediction, Game Preview, Live Stream, Odds & Picks
The Colorado Buffaloes hit the road to Seattle for a showdown against the No. 17 Washington Huskies. The Huskies are having an outstanding season at 8-2 and 5-2 in the Pac-12. They are on a four-game tear and slowly climbing the rankings.
Meanwhile, the Buffaloes are 1-9 and quite possibly the worst team in college football. In the last two weeks, against Oregon and USC, Colorado lost by a combined score of 104-27.

Predictably, Washington is heavily favored with a 31-point spread. The full-game total is 64.
Let’s check the latest college football odds, stats, injury reports and college football lines for Colorado vs Washington. We’ve plenty of NCAA football odds for you to consider.
Colorado Ready for Season to End
There isn’t much to say about a 1-9 team that you probably couldn’t figure out just by virtue of having one win in 11 weeks. At 2-7 against the spread, Colorado is also one of the worst bets in college football.
The Buffaloes got crushed by USC on Saturday 55-17, failing to cover as 34½-point underdogs along the way. It was the second straight game Colorado failed to cover as 30+ point favorites, and I see no reason to doubt that Washington will be number three.
Quarterback J.T. Shrout has just 1,100 yards and six touchdowns. That is bad enough, but Shrout’s seven interceptions make it significantly worse. Their leading rusher is Deion Smith, with a mere 381 yards and two touchdowns.
There is not much to talk about here; the Buffaloes are a 1-9 team that already had its big upset for the season and are rudderless in dangerous waters in Week 12.
Washington Massive Favorites
Washington moved to 8-2 overall after a nail-biting 37-34 victory over the Oregon Ducks. While the win was tight, Washington’s offense shined with 522 yards from scrimmage. Quarterback Michael Penix Jr. had his second 400+ yard game in four weeks, and he leads the nation in yards with 3,640. Penix is a Heisman Trophy candidate with 25 touchdowns and a passer rating of 155.5.
The Huskies have three receivers with 500+ receiving yards and two rushers north of 400 yards on the ground. Washington ranks 14th in scoring, 11th in total yards and leads the country in passing yards.
The No. 1 passing attack in college football should have no problems against a passing defense outside the top 100.
Colorado vs Washington Game Injuries
Colorado vs Washington Head-to-Head
In their last 10 head-to-head games, Washington is 8-2 straight up and 7-3 against the spread. However, Colorado won the previous two games, including 20-17 last season as 6½-point underdogs.
Colorado vs Washington Game Information
- Game: Colorado vs Washington
- Location: Husky Stadium, Seattle, WA
- Day/Time: Saturday, Nov. 19, 9 p.m. ET
- Colorado vs Washington Live Stream: ESPN
Colorado vs Washington Betting Lines
Colorado vs Washington Picks & Prediction
Colorado did manage a massive upset over Cal as 22-point underdogs, but lightning rarely strikes twice, and Washington is better than Cal. They failed to cover back-to-back weeks as 30+ point underdogs, and there is no reason to assume that changes on Saturday in Seattle. Washington is 1-0 as 30+ point favorites and 2-0 as favorites of 20 or more.
Don’t overthink this one and take Washington to dominate.