Louisville vs Kentucky Picks: Cardinals ATS Bet on November 30

Bettors get a generous line for the Louisville Cardinals, who square off against the struggling Kentucky Wildcats on Saturday.

College football lines have the visiting Cardinals at -4,despite looking good in winning three of their last four games. Therefore, we expect most of the money to come for the road team, which is seeking its eighth win of the season.

For Kentucky, it’s all about saving face and trying to rebuild.

Louisville vs Kentucky Game Information

• Game: Louisville (7-4) vs Kentucky (4-7)
• Date/Time: Saturday, Nov. 30, 12 p.m. ET
• Location: Kroger Field, Lexington, KY
• Louisville vs Kentucky Live Stream: Fubo.tv

Check all the college football news for injury updates before placing a bet on the game.

2 Keys to Bet on Louisville vs Kentucky

1. Stats Favor Cardinals Win

Winning on the road in college football isn’t easy, but we are firmly in favor of the Cardinals covering the NCAAF spread against the Wildcats.

They scored wins over Boston College and Clemson before losing 38-35 in a close game against Stanford. That came on the road, but they bounced back with a 37-9 win over Pittsburgh and that holds them in good stead this week.

It was a great day in The Ville to send Pitt back home!#GoCards #Louisville pic.twitter.com/SRZ3RmQCoT

— Cardinal Companion (@CardsCompanion) November 24, 2024

After opening at -3 favorites, we’re not surprised to see money come for the Cardinals, who have enough offensive power to blow the Wildcats off the field.

Quarterback Tyler Shough has been excellent, scoring 23 touchdowns with only six interceptions, so he could tear the Wildcats defense apart. It’s a Wildcats defense that allowed 48 points against Florida, and Louisville knows how to pile on the points.

“There’s no easy weeks. I think it’s a hell of a conference… The resolve in our locker room is good,” coach Pat Narduzzi said. “Our kids, they understand where they are. We got to make more plays, and we just didn’t start off fast like we needed to. It’s going to happen in the game of football.”

Bet Louisville -4 (-110)

2. Kentucky Hoping for Late Revival

It hasn’t been an easy year for the Wildcats, who fell to 4-7 when losing 31-14 to the Texas Longhorns last week.

They haven’t had an easy schedule, but with four losses from their last five games and their only win in that span coming against Murray State, it’s tough for bettors to find any confidence with the home underdog.

Most of the early money has been on Louisville, and that shows distrust with the betting public for the Wildcats despite the series history. Per Louisville vs Kentucky betting trends, the Wildcats have won the last five meetings.

Kentucky quarterback Cutter Boley went 10 of 18 with an interception last week, and it was a stuttering offense that couldn’t get anything going. To keep up with the Cardinals offense, they’ll need to start playing much better on that side of the ball.

That’s our biggest worry for the Wildcats, and it’s too much of a worry to include them in our NCAA football picks.

Touchdown Profits! Bet $200, Get $450 Bonus on first time deposit.

Over Best Bet for Louisville vs Kentucky

We have Louisville winning by at least one touchdown, so we’re including the -4 line in our college football predictions.

It’s one of our strongest bets of the week in college football, and we don’t see how the Wildcats will keep the Cardinals out of the end zone. Therefore, we’re also including over 49.

It should be a high-scoring game, especially for Louisville, which should do the majority of the scoring.

Bet on Over 49 (-110)

Questions of the Day

Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets.