NCAA Football Picks: 3 Best Big Ten Bets in Week 13
- Can Ohio State end Indiana’s dreams of an undefeated season?
- See why the over is a good pick in the Northwestern vs Michigan betting line.
- Check all the Big Ten odds at BetUS sportsbook.
When is the last time that those outside of Bloomington were more interested in an Indiana football game in November than the Week 13 showdown with Ohio State. With Oregon unlikely to stumble in its regular-season finale against Washington and Penn State favored to win its last two games, the loser of Saturday’s game between the Hoosiers and the Buckeyes might be out of the running for the Big Ten title game.

When looking at the college football odds, Illinois is a slight road favorite at Rutgers with a chance of the game going off as a Pick’em. Nebraska (-2.5) is the home favorite against Wisconsin while Iowa (-6.5) is favored on the road in the showdown with Maryland. Things get started on Friday with Michigan State favored by 13.5 points against visiting Purdue.
Four of the top nine teams in our odds to win the NCAAF national championship are Big Ten programs. Oregon and Ohio State come in at Nos. 1 and 2 in the College Football Playoff rankings with Penn State at No. 4.
Before we take a look at some of the best Big Ten bets in Week 13, make sure to check the latest college football news.
Touchdown Profits! Bet $200, Get $450 Bonus on first time deposit.
Top 3 NCAAF Picks for Big Ten in Week 13
1. Bet Over in Indiana vs Ohio State
Few would have thought that Indiana would have been part of one of the biggest Big Ten games when the season began. Well, the clash between the 10-0 Hoosiers and the 9-1 Ohio State Buckeyes is finally here.
Picking Ohio State to win doesn’t offer much value and going with the Buckeyes to cover as the 13-point favorites at home doesn’t feel like the safest option to bet online.
We’re headed back to The Shoe 🍿
See you soon for Indiana-Ohio State 👋 pic.twitter.com/hDAGzs43kQ
— College GameDay (@CollegeGameDay) November 16, 2024
The total is at 51.5 for the game. Per Indiana vs Ohio State stats, the Buckeyes and Hoosiers rank first and second in the Big Ten in total defense and both allow less than 14 points per game. Don’t be surprised to see the two offenses get going and for the game to land over the total.
Bet This Pick: Indiana vs Ohio State over 51.5
2. Take Minnesota to Cover vs Penn State
Looking at the teams, Penn State has the superior roster to Minnesota but that doesn’t always translate to what those who bet online when seeing these teams play.
A 6-4 Minnesota team doesn’t get much attention for the quality of its defense, but the Golden Gophers have allowed the fifth-fewest yards among Big Ten teams. Minnesota is in the top half of the Big Ten in red zone defense.
Penn State takes on Minnesota this weekend. We preivew the upcoming matchup plus recap the top five freshmen that stood out last weekend against Purdue.
Join us live at 10!
Join: https://t.co/lhnuGk262y
BWI Live: https://t.co/E3pzQuJGBu pic.twitter.com/lII6vVlkKl
— Blue White Illustrated (@PennStateOn3) November 20, 2024
Look for Penn State to add another win to its total but when looking for betting options, the +193 odds for neither team to score at least three times in a row is pretty tempting for NCAA football picks.
Bet This Pick: Neither Minnesota Nor Penn State Will Score Three Times In A Row (+193)
3. Northwestern vs Michigan to Go Over
Four of the last five games between Northwestern and Michigan went under the total. However, that could change this season as the Wolverines look to beat the Wildcats for the eighth time in a row.
The last time that Northwestern played at Michigan, the Wolverines won 33-7. With the way Michigan has played this year, bet the Wolverines to cover as home favorites at your own risk.
Instead, for college football predictions, note that the total of 36.5 is one of the lowest numbers this week and the game could land over the total.
Bet This Pick: Northwestern vs Michigan Over 36.5 (-110)
Questions of the Day
Who is the favorite to win the Big Ten?
Ohio State (-115) and Oregon (EV) lead the way in the odds of winning the Big Ten title.
Which Big Ten teams have the best record against the spread this season?
Indiana has covered in eight of 10 games with Minnesota 7-2-1 against the spread.
Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets.