Ohio vs Jacksonville State Prediction, Odds and Best Bet for Cure Bowl December 20
- Get the best Ohio vs Jacksonville State betting lines at BetUS.
- The StaffDNA Cure Bowl is on the line at Camping World Stadium.
- Most of the early money has come for the Gamecocks +3½ (-115)


Place your bets on Ohio vs Jacksonville State at BetUS Sportsbook!

The Ohio Bobcats and Jacksonville State Gamecocks battle for the StaffDNA Cure Bowl at Camping World Stadium on Friday, where college football lines have Ohio at -3½.
Ohio vs Jacksonville State Game Information
- Game: Ohio (10-3) vs Jacksonville State (9-4)
- Date/Time: Friday Dec 20, Noon ET
- Location: Camping World Stadium, Orlando, FL
- Ohio vs Jacksonville State Live Stream: Fubo.tv
Check updated Ohio vs Jacksonville State injuries before placing your bets.
2 Top Ohio vs Jacksonville State Picks: Best ATS and Over/Under Bets
1. Ohio ATS -3½ (-105)
The Bobcats will be buoyed by their 38-3 win over Miami (OH) and they have the most momentum entering the bowl game.
They are riding an impressive winning streak, which ended with a win in the MAC Championship, and despite playing on the road, we fancy their chances of covering the NCAAF line of -3½.
Most of the early money has come for the Gamecocks to hold down the fort in front of a home crowd, but we’re convinced the Bobcats are a better team. They haven’t been tested in their last five games, with the closest game being a 24-7 win over Toledo.
The Bobcats have arrived. ✈️#OUohyeah pic.twitter.com/AUpQpiAwZN
— Ohio Football (@OhioFootball) December 16, 2024
Jacksonville State has also been impressive at times, including a bounce-back 52-12 win over Western Kentucky, but we don’t think the 9-4 team is good enough to keep up with Ohio, especially following the Bobcats’ impressive MAC Championship win.
We would have been prepared to take -6½ with college football odds, and we can’t comprehend the money coming for the Gamecocks. They haven’t been beating overly tough opponents, and given the momentum Ohio has, we’re backing it to win the game and cover the spread.
Bettors get a generous -105 for Ohio to cover, so lock it in.
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2. Ohio vs Jacksonville State Over 54½
Our college football predictions today also feature over 54½, which is a high line, but we’re confident Ohio and Jacksonville State can produce the goods.
Quarterbacks Parker Navarro and Tyler Huff are capable of leading their teams down the field to score multiple touchdowns, and it could be a back-and-forth affair on the offensive end.
Ohio put up 38 points on Miami (OH), and although they only allowed three points, they could struggle to contain the Gamecocks’ offense, which scored 52 points against Western Kentucky.
We see Ohio and Jacksonville State gunslinging for the first half before Ohio pulls away in the fourth quarter to cover the spread.
Bet on Ohio vs Jacksonville State Over 54½
Questions Of The Day
What are the odds in the Ohio vs Jacksonville State game?
The Ohio Bobcats are -3½ favorites against the Jacksonville State on Friday.
When did Ohio last win a Bowl game?
Ohio won the 2023 Myrtle Beach Bowl 41-21 when beating Georgia Southern.
Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets