South Carolina vs Clemson NCAAF Picks: Gamecocks Get it Done November 30
- The South Carolina vs Clemson betting line has Clemson at -2 on Saturday.
- The Palmetto State rivalry game could be a College Football Playoff play-in.
- Early money has come for the Gamecocks to win the big one.
- Get the best Week 14 odds at the BetUS Sportsbook.


Place your bets on South Carolina vs Clemson at BetUS Sportsbook!

A close game is expected on Saturday between the South Carolina Gamecocks and Clemson Tigers, with NCAAF lines having Clemson favored at -2½. The contest could amount to a College Football Playoff play-in game, although South Carolina’s chances appear to be better than those of Clemson.
The Tigers moved into the rankings with three consecutive wins, but arguably South Carolina is playing better football after posting five straight victories.
The Clash of The Palmetto. South Carolina. Clemson. It’s deeper than hate. It’s a way of life. pic.twitter.com/MgCXoO9zJE
— General Will (@GamecockWill69) November 26, 2024
South Carolina vs Clemson Game Information
- Game: South Carolina Gamecocks (8-3) at Clemson Tigers (9-2)
- Date/Time: Saturday, Nov. 30, Noon ET
- Location: Memorial Stadium, Clemson, S.C.
- South Carolina vs Clemson Live Stream: Fubo.tv
Check all the college football news for injury updates before placing a bet on the game.
2 Keys to Bet on South Carolina vs Clemson
1. South Carolina Picked to Continue Win Streak
There has been good money for the Gamecocks to continue their winning streak approaching bowl – or playoff – season.
They have won their last five games against the likes of Oklahoma, Texas A&M and Vanderbilt, so they have been beating solid teams. The 28-7 victory over Vanderbilt was an excellent display of quality college football, and money is coming for them to take down another good team.
College football odds have the Gamecocks at +105 to win outright, and the +2½ line has been backed into -110. Money continues to come for the road team, and beating Clemson at Memorial Stadium would be a massive scalp in the eyes of playoff selectors.
Their last road win came over the Commodores by 21 points, and the Commodores have played well at times in 2024. It’s a high-ranking win and we expect that form to carry over to Week 14.
Bet South Carolina moneyline (+105)
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2. Tigers Hanging Tough
It hasn’t been a vintage year for the Tigers, but they have bounced back from a loss to Louisville with three consecutive wins over Virginia Tech, Pittsburgh and The Citadel.
They improved to 9-2, which is a solid record, and although they’re not as strong as they used to be, they are being respected with online betting odds at -2 against the red-hot Gamecocks.
We have been mightily impressed with quarterback Cade Klubnik, who has put himself in contention for end-of-year awards. He owns 29 touchdowns and only four interceptions, and he’s often the difference for the Tigers.
Following a win over Virginia Tech, though, coach Dabo Swinney wasn’t pleased.
“Just stuff that we needed him to do as a quarterback and decisions,’’ Swinney said. “He took four sacks, every sack was on him, and none of them should have happened. He just tried to do a little too much a couple times, just frustrating, (and) there were a couple of plays there that we didn’t pull the trigger on.”
Despite his harsh words, Klubnik is a top-quality player and he is why Clemson is being respected in the market. However, one player doesn’t make a team, and Clemson needs to be much better to hold off the Gamecocks.
Best Bet for South Carolina vs Clemson
We expect a close and tense game, but our college football picks have South Carolina scoring its biggest win of the year.
The Gamecocks have passed multiple tough road tests in 2024, including wins over Oklahoma and Vanderbilt, and they’re built to beat the Tigers. They should put pressure on the offensive line and force Klubnik into making mistakes.
Per South Carolina vs Clemson betting trends, the Gamecocks have lost eight of the last nine in the series, but they did win at Clemson in 2022.
We’re including under 49 in our picks. It should be a low-scoring game where defense plays its part, and a same-game parlay is in order.
Bet on South Carolina vs Clemson Under 49 (-110)
Questions Of The Day
What are the odds in the South Carolina vs Clemson game?
The Clemson Tigers are -2 favorites (-125 moneyline) against the South Carolina Gamecocks (-105) on Saturday.
Who won the most recent meeting between South Carolina and Clemson?
Clemson leads the series 73-43-4 following a 16-7 victory in 2023.
Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets