Virginia vs Clemson Picks 10/19: Bet Tigers ATS and Under
- Clemson will be looking to move to 6-1 with a strong conference win against Virginia.
- Virginia head coach Tony Elliott will make his first visit to Clemson after 11 years working for Clemson’s Dabo Swinney.
- Will Virginia’s defense keep up with Clemson’s dominant high-octane offense?
- BetUS Sportsbook has the Tigers as 21-point favorites to win.
Dabo Swinney and the No. 10 Clemson Tigers, strong college football betting odds favorites, will have a very special visit this coming weekend when their ACC rivals, the Virginia Cavaliers, show up to “Death Valley” with head coach and former Clemson offensive coordinator Tony Elliott at the helm.

Coming off a 49-14 win over the Wake Forest Demon Deacons, Clemson will look to put sentiments aside quickly and make quick work of a Cavaliers team that lost 24-20 to the Louisville Cardinals last weekend.
With the spread set at 21 points, will the Tigers be able to roll to an easy win, or will Elliott have a plan ready for his former team, including pulling off a shocking NCAAF betting upset?
Virginia vs. Clemson Game Information
- Game: Virginia (4-2, 2-1 ACC) vs Clemson (5-1, 4-0)
- Date/Time: Saturday, Oct. 19, Noon ET
- Venue: Frank Howard Field at Memorial Stadium, Clemson, South Carolina
- Virginia vs. Clemson Live Stream: ACC Network
Virginia vs. Clemson Betting Odds and Spreads
Virginia vs. Clemson Betting Trends
- Clemson is 4-2-0 ATS this season.
- Virginia is 4-1-1 ATS this season.
- Clemson is 3-0-0 ATS as home favorite this season.
- The total has gone over in three of Clemson’s six games this season.
- The total has gone under in four of South Carolina’s six games this season.
My Top Virginia vs. Clemson Betting Picks
Pick Tigers ATS In Dominant ACC Showing
Throughout the season, Clemson has continuously shown itself to be one of the best and most balanced college football teams, especially on offense. In just the last two games, the Tigers have managed to stack upwards of 500+ total yards on offense without any of the two attacking phases, rush or pass, taking a noticeable majority above the other.
Now, I know what you may be thinking. Virginia’s defense has also been holding its own, especially when defending the run. It is among the 50 best run defenses in the country, allowing a mere 123 rushing yards per game, and could be a nightmare for Clemson’s top rushers, Phil Mafah and quarterback Cade Klubnick.
But the same can’t be said about the Cavaliers’ defense against the pass, allowing an average of 260.5 yards, and that is where the Tigers should focus their attack to secure a relatively easy home win and cover the college football betting spread set for this game.
309 yards. 21 TDs on the year.@CadeKlubnikQB is getting things done👊 pic.twitter.com/PTDjkhYuLe
— ACC Football (@ACCFootball) October 14, 2024
I’ll admit, considering the level of play both teams have shown thus far, the 21-point spread seemed a bit outlandish for a second. But then, considering Clemson is scoring an average of 41 points this season and allowing 21.7, that’s a 20-point difference right there, which makes picking Clemson ATS as your first online betting pick here a lock.
Once Clemson can get its passing game going, especially early in the game, and manage the clock in its favor while keeping Virginia’s offense off the field as much as possible, the Tigers should find no issue scoring the dub and moving to 5-1.
Pick: Clemson -21 (-110)
Touchdown Profits! Bet $200, Get $450 Bonus on first time deposit.
With Both Defenses Balling, Bet the Under
According to college football news and rumors sites, one of the main storylines behind Virginia’s visit to Clemson this weekend will be Tony Elliot’s first visit to his former university, this time as head coach of the Cavaliers.
Having spent 11 seasons under Dabo Swinney’s tutelage as an assistant and as the team’s offensive coordinator for the past seven seasons, during which time he was a crucial component in Clemson’s six College Football Playoff appearances, four national title games and two national championships, Elliot knows all the ins and outs behind the Tigers’ attack.
Dabo Swinney talks about relationship with Tony Elliot. #Clemson #ClemsonFootball pic.twitter.com/rv8sLEUvyT
— Clemson Sports Media (@CUSportsMedia) October 16, 2024
Between that and Clemson’s defense playing at an overwhelmingly dominant pace, it feels safer and safer to consider taking the under here as the second NCAAF bet for this game. While 57 ½ points seem like a doable number for Clemson’s offense to achieve with a bit of help from the Cavaliers, I don’t see this game being an utter blowout.
Yes, there will be plenty of offensive fireworks, and Clemson looks like a team that will easily score 40+ again this weekend, but playing it safe and focusing on landing a strong college football odds win, consider the betting trends for this game and bet the under.
Pick: Under 57 ½ (-110)
Questions of the Day
What are Cade Klubnick’s Heisman Odds?
Clemson QB Cade Klubnick currently has +1200 odds to win the 2024-25 NCAAF Heisman Trophy
Who Is Virginia Playing After Clemson?
After they visit Clemson, Virginia will play host to UNC in Week 9.
Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets.