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Virginia vs Syracuse Prediction, Game Preview, Live Stream, Odds & Picks

Orange Host Cavaliers in Huge ACC Clash

Syracuse Looking to Stay Perfect

It’s been a fast start to the 2022 college football season for the Syracuse Orange, but now the real tests begin. Syracuse hosts the Virginia Cavaliers on Friday night and the ACC rivals could be in for a great matchup.

Virginia came into the 2022 season with big expectations, but things haven’t gone well for the Cavaliers. They are 2-1 but a blowout loss to Illinois in Week 2 has them trying to get back on track.

Brennan Armstrong #5
Brennan Armstrong #5 | Justin casterline/getty images/afp

Syracuse comes into Week 4 with a perfect 3-0 record, and the Orange have exceeded expectations. The Orange blew out Louisville in Week 1 and stunned Purdue last weekend to stay undefeated.

The college football odds for this game have the Syracuse Orange as 10-point betting favorites.

Let’s check the latest NCAAF picks, stats, injury reports, and NCAAF odds for Virginia vs Syracuse. We’ve plenty of NCAAF predictions for you to consider.

Cavaliers Can Get Some Stops

The Virginia Cavaliers have not shown that they have an offense that can win in a shootout, but the defense can be dominant. The Cavaliers are giving up just 18 points per game, but they also have an offense averaging just 17 points.

Quarterback Brennan Armstrong has to find a way to be more accurate as he has thrown three interceptions to just two touchdowns. Armstrong has completed just 40 percent of his passes on the road.

The Cavaliers do have a talented secondary, and that unit will need to step up in this one. Look for Virginia to try and pressure the quarterback in an attempt to slow down a talented Syracuse offense.

Syracuse Playing Fast on Offense

Syracuse Orange needed some magic to pull off a 32-29 win in Week 3 against Purdue, but it’s the type of win that could propel them to go on a big run. After the win, head coach Dino Babers said, “To win a game like that, to have the scoreboard go back and forth from the third quarter to the fourth quarter, through the highs and lows. … There were turns, there were deep valleys and then there were big climbs.”

The Orange have been a great offensive team that is averaging 37 points. Quarterback Garrett Shrader has set the tone as he has thrown eight touchdown passes to no interceptions.

Syracuse has also been able to get big stops on defense despite giving up 29 points in Week 3. The Orange are allowing less than 100 rushing yards per game, and that unit will be a big key in this game.

Virginia vs Syracuse Head-to-Head

Since this is a conference matchup, you will get some help when looking at recent scores and odds in this head-to-head matchup. Virginia holds a 3-2 lead in the all-time series, and has rattled off those three wins in a row.

Virginia vs Syracuse Game Information

  • Game: Virginia (2-1) vs Syracuse (3-0)
  • Location: JMA Wireless Dome, Syracuse, NY
  • Day/Time: Friday, Sept. 23, 7 p.m. ET
  • Virginia vs Syracuse Live Stream: ESPN

Virginia vs Syracuse Betting Lines

Virginia vs Syracuse Prediction

Making college football picks gets a bit more interesting once conference action starts, and this should be a great way to start things off in the ACC. It’s been a great start to the season for Syracuse, but Virginia would love to spoil that run.

The offense of Syracuse has been on a roll to begin the year, but it is going to face a great defense from Virginia. The Cavaliers won’t be able to completely slow down the Orange on Friday night, but they will get enough stops to keep this a one-possession game throughout.

Head to BetUS Sportsbook and take the 10 points and bet on the Virginia Cavaliers as they provide a great challenge to the Syracuse Orange in a loss.

Virginia vs Syracuse Edge

Virginia vs Syracuse Results

Virginia vs Syracuse Game Injuries

Virginia vs Syracuse Game Summary

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