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Wake Forest vs Louisville Prediction, Game Preview, Live Stream, Odds & Picks

The 10th-ranked (tied) Wake Forest Demon Deacons travel to Louisville to take on the Cardinals in an ACC Atlantic Division contest. Wake is aiming to earn a berth in a prominent bowl game, while Louisville eyes an underdog NCAA football odds payout. Wake Forest vs Louisville is scheduled at 3:30 p.m. ET Saturday afternoon, with Cardinal Stadium as the venue.

Let’s check the latest college football odds, stats, injury reports and college football lines for Wake Forest vs Louisville. We’ve plenty of College football odds for you to consider.

Sam Hartman #10 of the Wake Forest Demon Deacons runs with the ball against the Louisville Cardinals on October 27, 2018
andy lyons / getty images north america / getty images via afp

Wake Forest Demon Deacons

The Wake Forest University Demon Deacons are ranked T10 in the nation, 6-1 (2-1 in ACC) Both Wake and the Syracuse Orange are chasing prohibitive favorite Clemsin the ACC Atlantic. The Deacons are on a roll, perfect against the spread in their last four games and 9-1 ATS in games held on field turf.

Wake Forest ranks 37th nationally in total offense (3,071 yards, 438.7 yards/game, 6.11 yards/ play). They have scored 36 offensive touchdowns, led by junior quarterback Sam Hartman (1,755 yards, 21 touchdowns, three interceptions). The Demon Deacons’ rushing attack is paced by sophomore Justice Ellison, (432 yards, 4.8 yards/carry, three touchdowns).

In online sports betting, the Demon Deacons are 6-1 against the spread this season.

Louisville Cardinals

The Louisville Cardinals enter with a 4-3 record (2-3 in conference). They rank 55th in total offense (2,935 total yards, 419.3 yards/game, six yards/play, 419.3 yards per game. They have a total of 22 offensive touchdowns. In your betting online, note that while Louisville moves the ball, it’s not getting to the end zone.

Louisville is led by senior quarterback Malik Cunningham (1.090 yards, five touchdowns, four interceptions). Cunningham also leads with 503 rush yards (80 carries, 6.3 yards.carry, nine touchdowns).

Louisville is 4-3 ATS against college football spreads this season.

Wake Forest vs Louisville Game Injuries

Wake Forest vs Louisville Head-to-Head

Louisville leads the series with Wake, 6-3, dating back to 2007. Louisville and Wake Forest have played every year since 2014, dividing the last four. Wake was a 37-34 winner in the last game.

Wake Forest vs Louisville Game Information

  • Game: Wake Forest (6-1) vs Louisville (4-3)
  • Date/Time: Saturday, October 29th, 2022, 3:30 p.m. ET
  • Location: Cardinal Stadium, Louisville, KY
  • Wake Forest vs Louisville Live Stream: ESPN

Wake Forest vs Louisville Betting Lines


Wake Forest vs Louisville Prediction

Wake Forest should be the betting favorite heading into this intra-division game. The Demon Deacons have far more riding on the outcome, and the better team overall. Wake will be relying on its defense to keep Malik Cunningham in check.

We are picking Wake Forest to defeat Louisville Saturday afternoon. We’re not sure about the total points in this game, but we do like Wake Forest on the moneyline and to cover the spread.

The odds and predictions in the article are based on the time of writing and publication. They may differ as to when the actual event takes place.

Wake Forest vs Louisville Edge

Wake Forest vs Louisville Results

Wake Forest vs Louisville Game Summary

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