Cleveland Guardians vs San Diego Padres Prediction, Picks and Odds 04-02-2025

Note: Manzardo is sidelined due to family emergency list, and he is likely to miss two to three games.

Note: Thomas left the last game in between due to mild plantar fasciitis symptoms, and it remains to be seen if he will be active against the Tigers on Sunday.

Note: Ortiz has been placed on paid leave by the league while he is under investigation for gambling.

Note: Arias exited the matchup with a left ankle sprain, and it is unclear if he will suit up against the Cubs on Tuesday.

Note: Ramirez left the game after getting hit by a pitch on his forearm, and it is unclear if he will be active for Friday's game against the Cardinals.

Note: Hedges has been placed on the 7-day injured list due to a concussion, and there is no timetable for return.

Note: Walters has been added on the 15-day IL due to a Lat injury, and it is unknown how long he will be debilitated.

Note: Thomas has been placed on a 10-day injured list due to a foot injury, and he will miss an undetermined length of time.

Note: Kwan left the game due to a right wrist inflammation, and it remains to be seen if he will be active against the Angels on Friday.

Note: Cecconi is managing a groin injury, and he is unlikely to face the Dodgers on Wednesday.

Note: Santana has been sidelined due to due to left leg tightness, and it is unknown if he will play Monday versus Dodgers.

Note: Gaddis is laid up for a personal reason, and team officials have yet to provide an exact return date.

Note: Brennan has been placed on the 10-day injured list with left forearm inflammation, and he will miss an undetermined length of time.

Note: Lively left the previous game due to an forearm injury, and it is unknown if he will face the Brewers on Tuesday.

Note: Bibee exited the last game due to apparent leg cramping, it is unclear if he will suit up against the Nationals on Monday

Note: Cecconi has been dealing with a left oblique strain, but has began his rehab assignment.

Note: Ramirez left the contest due to a leg injury, and it remains to be seen if he will be active against the Blue Jays on Saturday.

Note: Sewald has landed on the 15-day injured list due to a right shoulder strain, and it is unknown if he will return to action.

Note: Clase is dealing with a shoulder injury, and it is unclear if he will dress against the Red Sox on Friday.

Note: Thomas has been ticketed to the 10-day injured list with a right wrist bone bruise, and he will be sidelined till the late part of April.

Note: Thomas exited the contest with a right wrist contusion, and it is unclear if he will take the field against the White Sox on Thursday.

Note: Ramirez left the match due to a sprained right wrist, and it remains to be seen if he will suit up against the Royals on Sunday.

Note: Bibee is ailing from illness, and it is unclear if he will face Royals on Saturday.

Note: Cecconi has been placed on the 15-day injured list with a left oblique strain, and a timetable for return has yet to be established.

Note: Means has been placed on the 15-day injured list with a elbow injury, and a timetable for return has yet to be established.

Note: Sabrowski has been ticketed to the 15-day injured list with a elbow injury, and there is no timetable for return.

Note: DeLauter underwent hernia surgery, and he will miss an undetermined length of time.

Note: Aleman will miss an undetermined length of time with an abdominal injury, and he will miss an extended period.

Note: Fry landed on the 60-day injury list after suffering an elbow injury, and he will miss an undetermined length of time.

Note: Hentges landed on the 60-day injury list after undergoing a right shoulder anterior capsule repair, and he will miss an undetermined length of time.

Note: Bieber is recovering from an elbow injury, and he will miss an undetermined length of time.

Note: Stephan is recovering from right UCL reconstruction surgery, and a timetable for return has yet to be established.

Note: Bergert exited the last matchup due to a forearm injury, and it is unknown if he will face the Nationals on Wednesday.

Note: Bogaerts is out of lineup due to a left shoulder soreness, and he is not projected to face the Reds on Friday.

Note: Suarez is facing a two games suspension, and it remains to be seen if he will be active against the Reds on Saturday.

Note: Merrill exited the previous game due to a head injury, and it is undetermined if he will suit up against the D-backs on Sunday.

Note: Arraez is dealing with a knee soreness, and it is unknown if he will play Friday versus Brewers.

Note: Bogaerts is managing with a left shoulder soreness, and it has yet to be determined if he will participate against the Brewers on Friday.

Note: Sheets left the last match due to an undisclosed injury, and it has yet to be established if he will be available against the Giants on Monday.

Note: Heyward has been landed on the 10-day injured list due to a left oblique strain, and he will remain out of the lineup until the early part of June.

Note: King has been out of lineup due to right shoulder stiffness, and it is unclear if he will play Braves on Sunday.

Note: Merrill is ailing with an illness, and it remains to be seen if he will return to action against the Angels on Monday.

Note: Cease left the last game due to an forearm injury, and it is unknown if he will play Friday versus the Rockies.

Note: McCoy has landed on the 10-day injured list due to a sprained finger on his left hand, and he will be sidelined till mid of May.

Note: Gillaspie has been placed on the 15-day injured list with an Oblique injury, and there is no timetable for recovery.

Note: Arraez is placed on the 7-day injured list with a concussion, and he will miss an undetermined length of time.

Note: Heyward is dealing with a knee injury, and it is unclear if he will play against the Astros on Saturday.

Note: Lockridge has been placed on the 10-day injured list with a left hamstring strain, and there is no timetable for recovery.

Note: Cronenworth exited the contest due to cramping in his ribs, and it remains to be seen if he will return to action against the Athletics on Wednesday.

Note: Tatis exited the matchup with a left shoulder discomfort, and it is unknown if he will play against the Athletics on Wednesday.

Note: Merrill has been placed on the 10-day injured list with a right hamstring strain, and there is no timetable for recovery.

Note: Machado exited the game due to calf tightness, and it is unclear if he will face Braves on Sunday.

Note: Brito has been landed on the 15-day injured list with right forearm strain, and team officials have yet to provide an exact return date.

Note: Waldron has been placed on the 15-day injured list with a Left oblique muscle strain, and team officials have yet to provide an exact return date.

Note: Darvish is bothered by an elbow injury, and team officials have yet to provide an exact return date.

Note: Hoeing is nursing a sore right shoulder, and he is not expected to feature in the lineup for the opening day contest against the Braves on March 27th.

Note: Reynolds is dealing with a stress reaction in his right foot, and he is not expected to suit up for the opening day matchup against the Braves on March 27th.

Note: Musgrove will miss an extended period due to Tommy John surgery he underwent in October, and he is without a definitive timetable for return.