Detroit Tigers vs St. Louis Cardinals Prediction, Picks and Odds 05-21-2025

Note: Guenther has been placed on the 60-day injured list due to a left hip arthroscopy, and he will miss an extended period.

Note: Torres exited the last game in between due to a neck contusion, and it has yet to be established if he will suit up against the Guardians on Sunday.

Note: Gipson-Long has been placed on the 15-day injured list due to a neck strain, and there is no timetable for his recovery.

Note: Carpenter left the game in between due to a right hamstring injury, and his availability against the Nationals is unknown on Tuesday.

Note: Mize left the game due to right leg cramping, and it remains to be seen if he will be active against the Athletics on Tuesday.

Note: Vest exited the game due to an undisclosed injury, and it is unclear if he will play Tuesday versus Pirates.

Note: Carpenter exited the game due to a right hamstring injury, and won't play against the White Sox on Thursday.

Note: Foley has been added to the 60-day injured list after undergoing surgery on his shoulder, and he will miss an extended period.

Note: Jackson has been placed on the 15-day injured list due to a flexor strain, and there is no timetable for return.

Note: Vierling has been added to the 10-day injured list due to a right shoulder inflammation, and he will miss an extended period.

Note: Olson has been placed on the 15-day injured list due to a right ring finger injury, and there is not timetable for return.

Note: Mize has landed on the 15-day injured list due to a hamstring injury, and there is no timetable for return.

Note: Torres is dealing with a hamstring injury, and it is uncertain if he will face the Angels on Saturday.

Note: Carpenter exited the matchup due to right hamstring soreness, and it remains to be seen if he will return to action against the Padres on Monday.

Note: Brebbia has been added to the 15-day injured list due to a right triceps strain, and he will be sidelined till early May.

Note: Brieske has hit the 15-day injury list due to a right ankle inflammation, and a timetable for recovery has yet to be established.

Note: Margot has been added to the 10-day injured list due to a left knee inflammation, and there is no timetable for return.

Note: Rogers is on the 10-day injured list due to a left oblique strain, and he will miss an undetermined length of time.

Note: Torres exited the matchup with a back injury, and it is unknown if he will play Monday versus Mariners.

Note: Madden has been ticketed for the 15-day injured list due to a shoulder injury, and he will miss an undetermined length of time.

Note: Perez is dealing with a lower back injury, and he will be sideline till the late part of April.

Note: Torres is dealing with a right quadriceps contusion, and it is unclear if he will suit up for the opening day contest against the Dodgers on March 27th.

Note: Meadows is dealing with a right arm injury, and it has yet to be determined if he will suit up for the opening day contest against the Dodgers on March 27th.

Note: Gipson-Long has been placed on the 60-day injured list with a Left hip injury, and he will miss an undetermined length of time.

Note: Vierling is dealing with a strained right rotation cuff muscle, and he is not projected to be active for the opening day contest against the Dodgers on March 27th.

Note: Baddoo underwent surgery to address a hamate bone fracture in his right hand, and team officials have yet to provide an exact return date.

Note: Lange has hit the 60-day injury list while recovering from late surgery, and a timetable for recovery has yet to be established.

Note: Cobb is dealing with right hip inflammation, and he isn't likely to be ready for the start of the season.

Note: Arenado left the game in between due to a sprained right index finger, and his availability against the Braves on Saturday is unknown.

Note: Arenado is dealing with a right shoulder impingement, and it has yet to be established if he will be active against the Nationals on Tuesday.

Note: Arenado is dealing with a finger injury, and it remains to be seen if he will face the Cubs on Friday.

Note: Contreras exited the game due to hand injury, and it is unclear if he will play Wednesday versus Pirates.

Note: Arenado exited the game due to a soreness in his right hand, and it is unknown if he will face the Pirates on Monday.

Note: Nootbaar is battling with a rib injury, and it is undetermined if he will dress against the Pirates on Monday.

Note: Nootbaar is bothered by an intercostal injury, and it is unknown if he will face the Guardians on Friday.

Note: Walker has been placed on the 10-day injured list due to appendicitis, and there is no timetable for his return.

Note: Herrera has been placed on the 10-day injured list due to a left hamstring strain, and there is no timetable for his return.

Note: Donovan left the previous game in between due to a toe injury, and it remains to be seen if he will be active against the Blue Jays on Wednesday.

Note: Liberatore exited the game due to fatigue, and it is unclear if he will face Dodgers on Friday.

Note: Walker has been placed on the 10-day injured list due to a left wrist inflammation, and there is no timetable for his return.

Note: Donovan is laid up with a hip injury, and it is unclear if he will play against the Orioles on Wednesday.

Note: Arenado is dealing with a ribs injury, and it is unknown if he will face Orioles on Tuesday.

Note: Contreras is nursing an undisclosed injury, and it remains to be seen if he will kit up against the Diamondbacks on Saturday.

Note: Arenado is battling with an back spasms injury, and it is uncertain if he will face the Nationals on Friday.

Note: Winn exited the contest with a left ankle sprain, and it is unclear if he will be active against the Pirates on Monday.

Note: Donovan is dealing with a ribs injury, and it is unknown if he will be active against the Braves on Wednesday.

Note: Winn exited the game due to lower back spasms, and it remain to seen if he will face Phillies on Saturday.

Note: Herrera has been added to the 10-day injured list due to a left knee injury, and he is without a definitive timetable for return.

Note: Gorman has been placed on the 10-day injured list with hamstring injury, and he will miss an undetermined length of time.

Note: Thompson has been placed on injured reserve with a a Grade 1 lat strain, and he will miss an undetermined length of time.