Houston Astros vs St. Louis Cardinals Prediction, Picks and Odds 04-16-2025

Note: Blanco is bothered by right elbow soreness, and it is unclear if he will play against the Mariners on Thursday.

Note: Altuve exited the last game due to a right hamstring tightness, and it is uncertain if he will be available against the Royals on Monday.

Note: Wesneski has been placed on the 15-day injured reserve with elbow injury, and he will miss an undetermined length of time.

Note: Alvarez is dealing with a hand injury, and it is uncertain if he will play against the Brewers on Monday.

Note: Abreu has been placed on the paternity list, and he is expected to miss two to three games.

Note: Rodgers is dealing with a hip injury, and it is unclear if he will play against Cardinals on Wednesday.

Note: Rodgers is battling with left hip soreness, and it is unclear if he will dress against the Angels on Sunday.

Note: Arrighetti has been landed on the 15-day with a fractured right thumb, and he will miss an extended period.

Note: Dubin has been lands on 15-day injured list with a right shoulder inflammation, and he will miss an undetermined length of time.

Note: France has been added to the 60-day injured list while recovering from right shoulder surgery, and he will miss an undetermined length of time.

Note: Wesneski suffered a left foot injury, and it remains to be seen if he will be active for the opening matchup against the Mets on Thursday.

Note: Whitley is hampered by a bone bruise in his left knee, and he is not expected to be active for the opening matchup against the Mets on Thursday.

Note: Walker is hobbled by a sore left oblique, and it remains to be seen if he will be active for the opening matchup against the Mets on March 27th.

Note: Leon is hampered by a Grade 1 left MCL strain, and he is not expected to be active for the opening matchup against the Mets on March 27th.

Note: Trammell will miss an extended period due to a calf injury, and team officials have yet to provide an exact return date.

Note: Ort is dealing with an oblique injury, and it is up in the air if he will dress against the Mets on March 27th.

Note: Garcia is fighting off an elbow injury, and he is not expected to be active for the opening matchup against the Mets on March 27th.

Note: Javier is nursing an elbow injury, and it is up in the air if he will dress against the Mets on March 27th.

Note: McCullers is dealing with a forearm injury, and he is not going to suit up for the opening contest against the Mets on March 27th.

Note: Arenado is battling with an back spasms injury, and it is uncertain if he will face the Nationals on Friday.

Note: Winn exited the contest with a left ankle sprain, and it is unclear if he will be active against the Pirates on Monday.

Note: Donovan is dealing with a ribs injury, and it is unknown if he will be active against the Braves on Wednesday.

Note: Winn exited the game due to lower back spasms, and it remain to seen if he will face Phillies on Saturday.

Note: Herrera has been added to the 10-day injured list due to a left knee injury, and he is without a definitive timetable for return.

Note: Gorman has been placed on the 10-day injured list with hamstring injury, and he will miss an undetermined length of time.

Note: Thompson has been placed on injured reserve with a a Grade 1 lat strain, and he will miss an undetermined length of time.