Milwaukee Brewers vs San Diego Padres Prediction, Picks and Odds 09-22-2025

Note: Frelick left the last game due to a left hamstring discomfort, and it is up in the air if he will be active against the Dodgers on Friday.

Note: Ashby has been placed on the paternity list, and he is expected to miss Sunday's game versus Nationals.

Note: Hoskins exited the game with a thumb injury, and it is unclear how long he will be debilitated.

Note: Zastryzny has been landed on the 15-day injured list with ribs stress reaction, and he will miss an extended period.

Note: Misiorowski exited the last game due to an ankle injury, and it is unknown if he will face the Cardinals on Friday.

Note: Cameron is placed on the paternity list, and he is expected to miss three to four games

Note: Woodruff has been transferred to the 60-day injured list with an elbow injury, and he is without a definitive timetable for return.

Note: Yelich is nursing a swelling in his right wrist, and it is unclear if he will take the field against the Cardinals on Thursday.

Note: Yelich exited the contest due to a right hand contusion, and it is undetermined if he will suit up against the Reds on Monday.

Note: Cameron exited the contest due to a left knee contusion, and it is undetermined if he will suit up against the Red Sox on Tuesday.

Note: Quintana is dealing with an arm injury, and it is unclear if he will suit up against the Guardians on Tuesday.

Note: Contreras is dealing with a finger injury, and it is uncertain if he will play against the Rays on Friday.

Note: Frelick exited the last game due to left knee discomfort, and it is unclear if he will be available against the Astros on Monday

Note: Peralta exited the matchup due to groin soreness, and it is undetermined if he will take the field for Monday's clash against the Astros.

Note: Collins left the game due to elbow injury, and it remain to seen if he will face the Cubs on Friday.

Note: Mitchell has been placed on the 10-day injured list with a left oblique tightness, and there is no timetable for return.

Note: Thomas has been ticketed on 15-day injured list with left elbow arthritis, and he will miss an extended period.

Note: Cortes is placed on the 15-day injured list with a elbow injury, and there is no timetable for recovery.

Note: Civale has been added to the 15-day injured list due to a strained left hamstring, and he will miss an extended period.

Note: Myers has been on the 15-day injured list due to a left oblique strain, and he will miss an extended period.

Note: Mears is ailing with an illness, and he is not projected to suit up against the Yankees on March 27th.

Note: Hall has been placed on 60-days injured reserve with a left lat strain, and he will miss an extended period.

Note: Ashby sustained a left oblique strain, and it has yet to be determined if he will suit up for the opening day matchup against the Yankees on March 27th.

Note: Perkins is dealing with a right leg fracture, and he will remain out of the lineup until the end of May.

Note: Gasser has been placed on 60-days injured reserve with a elbow injury, and he will miss an extended period.

Note: Yelich is nursing a lower back injury, and it remains to be seen if he will return to action against the Yankees on March 27th.

Note: Woodruff is managing a shoulder injury, and it is up in the air if he will take the field for the opening contest against the Yankees on March 27th.

Note: Sheets is dealing with personal reasons, and it is unclear how long he will be idle.

Note: Bergert exited the last matchup due to a forearm injury, and it is unknown if he will face the Nationals on Wednesday.

Note: Bogaerts is out of lineup due to a left shoulder soreness, and he is not projected to face the Reds on Friday.

Note: Suarez is facing a two games suspension, and it remains to be seen if he will be active against the Reds on Saturday.

Note: Merrill exited the previous game due to a head injury, and it is undetermined if he will suit up against the D-backs on Sunday.

Note: Arraez is dealing with a knee soreness, and it is unknown if he will play Friday versus Brewers.

Note: Bogaerts is managing with a left shoulder soreness, and it has yet to be determined if he will participate against the Brewers on Friday.

Note: Sheets left the last match due to an undisclosed injury, and it has yet to be established if he will be available against the Giants on Monday.

Note: Heyward has been landed on the 10-day injured list due to a left oblique strain, and he will remain out of the lineup until the early part of June.

Note: King has been out of lineup due to right shoulder stiffness, and it is unclear if he will play Braves on Sunday.

Note: Merrill is ailing with an illness, and it remains to be seen if he will return to action against the Angels on Monday.

Note: Cease left the last game due to an forearm injury, and it is unknown if he will play Friday versus the Rockies.

Note: McCoy has landed on the 10-day injured list due to a sprained finger on his left hand, and he will be sidelined till mid of May.

Note: Gillaspie has been placed on the 15-day injured list with an Oblique injury, and there is no timetable for recovery.

Note: Arraez is placed on the 7-day injured list with a concussion, and he will miss an undetermined length of time.

Note: Heyward is dealing with a knee injury, and it is unclear if he will play against the Astros on Saturday.

Note: Lockridge has been placed on the 10-day injured list with a left hamstring strain, and there is no timetable for recovery.

Note: Cronenworth exited the contest due to cramping in his ribs, and it remains to be seen if he will return to action against the Athletics on Wednesday.

Note: Tatis exited the matchup with a left shoulder discomfort, and it is unknown if he will play against the Athletics on Wednesday.

Note: Merrill has been placed on the 10-day injured list with a right hamstring strain, and there is no timetable for recovery.

Note: Machado exited the game due to calf tightness, and it is unclear if he will face Braves on Sunday.

Note: Brito has been landed on the 15-day injured list with right forearm strain, and team officials have yet to provide an exact return date.

Note: Waldron has been placed on the 15-day injured list with a Left oblique muscle strain, and team officials have yet to provide an exact return date.

Note: Darvish is bothered by an elbow injury, and team officials have yet to provide an exact return date.

Note: Hoeing is nursing a sore right shoulder, and he is not expected to feature in the lineup for the opening day contest against the Braves on March 27th.

Note: Reynolds is dealing with a stress reaction in his right foot, and he is not expected to suit up for the opening day matchup against the Braves on March 27th.

Note: Musgrove will miss an extended period due to Tommy John surgery he underwent in October, and he is without a definitive timetable for return.