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MLB Fantasy Week 22: It’s Playoff Time Picks!

For most MLB Fantasy leagues, Week 22 is the first week of the playoffs. So, if you’re reading this, congratulations because you haven’t yet been eliminated. For the rest of you, this guide will still help you win consolation games and better luck in 2024.

With so much on the line, and every week a must-win, let’s forgo the chit-chat intro and get right down to the best MLB picks you can make this week in fantasy.

MLB Fantasy Week 22: It’s Playoff Time Picks!
Eddie Rosario #8 of the Atlanta Braves | Alex Slitz/Getty Images/AFP

Props to Surging Hitters

The first name I want to highlight is Eddie Rosario from the Atlanta Braves. Owned in around 25% of leagues, Rosario was the fourth-best hitter over the last seven days with a batting average of .524 with three home runs and 10 RBI in 21 at-bats.


Week 22 brings two decent matchups for Rosario to continue his hot streak in the New York Mets and San Francisco Giants.

The Mets are up first, starting Monday night, with David Peterson (3-7, 5.45 ERA) on the mound for game one. Peterson is just one example of why the Mets’ season is in the toilet, and their pitching staff ranks 19th in both batting average and home runs.

If Rosario is taken and you need to dig deeper, consider DJ Steward, who is owed in less than 2% of leagues. The Utility player from the Mets has a less-than-impressive .224 average this season but hit .353 last week with three multi-hit games and three home runs.

Regarding MLB lines for Steward, he is -145 to go over 0.5 hits against the Braves on Monday night.

Playoff Pitching Picks

The playoffs separate the contenders from the pretenders. To win, you must have a stable of solid hitters and pitchers. This late into the season, guys begin to wear down and I’ts advisable to be quick on the draw when dropping slumping players. Pitchers need time to get back in the groove after a slump, and you won’t have time to wait with just a couple of weeks left before the final matchup.

Zack Littell is a guy I’m keeping my eye on as a candidate to fill one of my SP roster spots this week. The Rays once again showed us that they know pitching talent and made squeezed water from this rock.


Littell has delivered positive results in his first four starts thanks to pinpoint accuracy and a strategy of pounding the strike zone. Littell is slated to make two starts this week, one against the Colorado Rockies and one against the New York Yankees. He has a fantastic 2.55 ERA in his last three starts and a strikeout-to-walk rate of 11-to-1.

The MLB odds for Tampa Bay’s series were not available, but the Rockies’ World Series odds are tied for the worst in the league at +100000; expect the Rays (+1000) to have a significant edge.

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