Surprising Giants Lead Best Run Line Teams
The San Francisco Giants were not expected to challenge for much of anything in the National League West this season.
The defending World Series champion Los Angeles Dodgers and revamped San Diego Padres were widely expected to be the best in the NL West this season, but San Francisco has far surpassed expectations at this point.

The Giants (42-25) are in first place in the division, a game ahead of the Dodgers and five games up on the Padres. Not only that, but Frisco has been a cash cow when it comes to cashing in against the MLB Run Line betting odds.
Will San Francisco be able to keep up their high level of play all season long to challenge for the NL West title? Will the Giants continue to bring home the bacon at a high rate when it comes to the MLB Run Line? The MLB betting odds for Wednesday’s entire slate of action are live in the BetUS online sportsbook right now.
Best In the Business
San Francisco Giants (43-24 RL)
San Francisco has recorded the best Run Line record in the league so far by ranking an encouraging 10th in scoring (4.67 RPG) and even more impressive fifth in team ERA (3.25). The Giants have gotten the job done against the Run Line odds no matter where they play by going 17-12 RL at home and a blistering 26-12 RL on the road. Keep any eye on San Francisco as a Run Line pick when they hit the road moving forward. It’s that simple.
Tampa Bay Rays (43-25 RL)
If you thought Tampa Bay’s American League East title and run to the 2020 World Series was an aberration, think again. The Rays (43-24) are in first place in the AL East, two games up on Boston. Tampa Bay has covered the Run Line odds at a consistent rate by ranking seventh in scoring (4.90 RPG) and sixth in team ERA (3.26). The Rays had covered the Run Line in four straight until falling to the White Sox 3-0 on Tuesday night. Tampa Bay has the best Run Line road mark in the majors (26-9) and looks like a team that isn’t going to give up their American League pennant easily – if at all.
Chicago White Sox (39-28 RL)
The White Sox (41-25) sit atop the AL Central standings, 4½ games up on second-place Cleveland. After getting off to a modest 9-9 start over its first 18 games, Chicago has picked up the pace nicely and has become a Run Line “beast” in the process. Since May 27, Chicago is 14-5 over its last 19 games.
The White Sox rank sixth in scoring (4.97 RPG) and fourth in team batting average (.253). Defensively, Chicago ranks a stellar third in team ERA (3.15) and sixth in quality starts (28). The White Sox have covered the Run Line odds in four of their last six heading into Wednesday’s series finale against Tampa Bay.
Seattle Mariners (39-30 RL)
The Mariners (34-35) are in third place in an AL West that has been surprisingly good with Oakland and Houston looking like legitimate pennant contenders and the Mariners and Los Angeles Angels floating around .500. Seattle is cashing in against the Run Line at a decent rate despite ranking 22nd in scoring (3.99) and 21st in team ERA (4.50).
The Mariners have won three straight heading into Wednesday night’s series finale against Minnesota. Seattle has put 20 runs on the board during its three-game winning streak and bashed the Minnesota Twins senseless en route to a stunning 10-0 shutout on Tuesday night.
Milwaukee Brewers (38-29 RL), Chicago Cubs (38-29 RL)
The Brewers and Cubs are tied for first in the NL Central with identical 38-29 marks heading into Wednesday night. Milwaukee hasn’t been hitting the ball well, ranking 21st in scoring (4.00 RPG) and 30th in team batting average (.210), but the Brewers have gotten some nice production out of their pitching staff this season. The Brewers are ninth in team ERA (3.62), eighth in WHIP (1.17) and third in quality starts (30).
Chicago has been a relatively well-balancedclub so far this season in ranking 11th in scoring (4.54 RPG) and 10th in team ERA (3.68). The Cubs (20-14) are one of just three teams with at least 20 Run Line covers at home, with the others being Colorado (23-13) and the cross-town White Sox (21-16).