2025 MLB Predictions: 5 Betting Locks to Make Playoffs

With projections from BetUS and a little common sense, here are the five teams you can bank on in October. 

Let’s dive into these MLB predictions and see who’s playoff-bound.

5 Best Bets to Make 2025 Playoffs

1. Dodgers (-10000): The Ultimate MLB Playoff Lock

The Los Angeles Dodgers are the final boss of the MLB right now. Popular sabermetric systems give them a ridiculous 99.2% shot at making the postseason. That’s what happens when your roster looks like an All-Star team with Shohei Ohtani, Mookie Betts and Freddie Freeman headlining. 

Their 104-win projection in MLB betting lines leads the league by a mile, and they have a 22% chance to repeat as World Series champs. Sure, some projections lean under 104 wins, but this team screams 100+ victories. Barring a miracle collapse, pencil the Dodgers into your MLB playoff bracket.

Bet on Dodgers to make the 2025 MLB Playoffs (-10000)

2. Yankees (-450) and Orioles: AL East’s Main Event

The New York Yankees and Baltimore Orioles are gearing up for another American League East slugfest. Projections peg the Yankees at 90 wins and the Orioles right behind at 89. Both squads look destined for October with Aaron Judge and Gunnar Henderson leading potential MVP campaigns. 

Despite some injury concerns, the AL East is stacked, but New York’s depth should secure a playoff spot. The O’s might retake the scenic Wild Card route, but either way, these two are October-bound. Keep an eye on this race — it’s the best drama MLB news will deliver all year.

Bet on Yankees to make the 2025 MLB Playoffs (-450)

3. Braves (-350): NL East’s Best Bet

Forget the Philadelphia Phillies’ 2024 division title and the New York Mets’ splashy signing of Juan Soto. The Atlanta Braves are the team to beat in the NL East. Projected at 92 wins, Atlanta is getting Ronald Acuña Jr. and Spencer Strider back healthy, which spells trouble for the NL East. 

Sabermetric systems love them, and with three teams projected at 88+ wins, this division is baseball’s ultimate slugfest. The Braves have better than a two-in-three shot at the playoffs, and given their roster depth, they’re a lock for October baseball. Plus, their MLB futures odds to win the division (+125) are still tasty if you move fast.

Bet on Braves to make the 2025 MLB Playoffs (-350)

4. Rangers (-135): Back in Business

After missing the playoffs in 2024, the reigning 2023 World Series champs are back with a vengeance. The Texas Rangers are projected for 89 wins, second-best in the AL behind the Yankees. With a deep lineup featuring Corey Seager, Marcus Semien and Adolis García, plus rotation aces Nathan Eovaldi and Jacob deGrom, Texas is primed for a postseason return. 

Projections put them at 81.2% playoff odds—an easy value at -135. The AL West is rugged, but the Rangers’ revamped bullpen and young stars give them the edge. Bet online on Texas securing that Round 1 bye.

Bet on Rangers to make the 2025 MLB Playoffs (-135)

5. Cubs (-165): NL Central’s New Kings

The Chicago Cubs are flipping the NL Central script. After finishing 10 games behind the Brewers last season, PECOTA projects Chicago at 91 wins — good for third-best in MLB. Led by new star Kyle Tucker, the Cubs have the fourth-best World Series odds (8%) behind the Dodgers, Yankees and Braves with an 89% chance to make the playoffs, and that’s hard to argue. 

The NL Central might be volatile, but Chicago’s mix of veterans and rising stars makes them the safest bet. Lock in the Cubs at -165 in MLB picks and parlays before the odds shorten.

Bet on Cubs to make the 2025 MLB Playoffs (-165)

Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets

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