Angels vs Padres Same Game Parlay Picks, Wednesday, 5/14: Bet San Diego (-1.5)

Those who play MLB bets and happen to like late-game heroics, the Los Angeles Angels vs San Diego Padres series is right up your alley and game-winning home runs in each of the first two games. The bullpens have allowed three home runs and 13 runs in less than 10 innings in the first two games as both games landed over the sports betting odds total.

The Angels are trying to win a road series versus the Padres for the first time in five years with veteran Kyle Hendricks set to be the starting pitcher for the Angels.

FINAL: Padres 6, Angels 4 pic.twitter.com/C1K9xYfGA3

— Los Angeles Angels (@Angels) May 14, 2025

The MLB odds list San Diego with +110 odds on the -1.5 moneyline. The Angels are priced at +159 to win on the road versus the Dodgers for just the second time in the last seven games.

There are some MLB parlay best bets to consider in Wednesday’s series finale. I’d tread carefully before placing MLB strikeout prop bets.

Top 3 Angels vs Padres Parlay Picks

1. Padres Run Line -1.5 (+115)

Perhaps if Mike Trout were available, I’d like the chances for the Angels to deliver as the road underdog. However, he is still working his way back from a knee injury.

Kyle Hendricks has struggled on the road and the last time he faced the Padres, he allowed seven runs in five innings. Keep that in mind when considering best MLB bets today.

Bet on Padres -1.5 (+115)

2. Jackson Merrill 1+ Runs + RBIs (-162)

The Padres are 11-5 this season with Jackson Merrill in the lineup. After missing a month, he came back with a vengeance with five straight multi-hit games before going hitless on Tuesday.

“The ceiling, legitimately, is he could be a Hall of Fame player…”

– @jonmorosi on 22-year-old Jackson Merrill’s potential pic.twitter.com/hpraBB6qi7

— MLB Network (@MLBNetwork) May 14, 2025

Even though he was 0-for-8 against the Angels last season, take a look at the -162 odds for Merrill to have 1+ Runs + RBIs when making MLB prop picks.

Bet on Jackson Merrill to have 1+ Runs + RBIs (-162)

3. Zach Neto to have 2+ Total Bases (+122)

Zach Neto is 3-for-8 with a pair of home runs in the first two games of this series. He took the second pitch of Tuesday’s MLB matchup out of the park. In his last four games against the Padres, he has a double and three home runs. That makes him somebody to consider when looking at MLB same-game parlay picks.

Bet on Zach Neto to have 2+ Total Bases (+122)

Angels vs Padres How to Watch

• Game: Angels (17-24) vs Padres (26-15)
• Date/Time: Wednesday, May 14, 9:40 p.m. ET
• Location: Petco Park, San Diego
• Angels vs Padres Live Stream: MLB.tv

Click here for Angels vs Padres stats.

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Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets.