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Angels vs Twins Prediction, Game Preview, Live Stream, Odds & Picks Sept. 23

Los Angeles, Minnesota Square Off In Battle of Slumping Clubs

Minnesota Has Lost Four in a Row

The Minnesota Twins will try to snap a four-game losing streak when they host the Los Angeles Angels in the first of a three-game weekend series on Friday night. Minnesota was swept by the Kansas City Royals in its last series and is in third place in the AL Central, 10 games behind the first-place Cleveland Guardians. Los Angeles has dropped three of four and is in fourth place in the AL West, a half-game behind the third-place Texas Rangers. Both teams could use a win, so check out our in-depth preview of Friday’s game before you make any bet online.

Let’s check the latest MLB picks, stats, injury reports, and MLB odds for Angels vs Twins. We’ve plenty of MLB predictions for you to consider.

Angels vs Twins Prediction, Game Preview, Live Stream, Odds & Picks Sept. 23
Angels vs Twins Prediction, Game Preview, Live Stream, Odds & Picks Sept. 23

Angels Giving Up Too Many Runs

The Los Angeles Angels have been unable to keep teams off the scoreboard of late, allowing 5.7 runs over their last four contests. The Angels have the 12th-best team ERA in baseball, but they haven’t been very solid over the last few games.

Hoping to change that will be right-hander Shohei Ohtani, who has been very good in the follow-up to his AL MVP season a year ago. Ohtani is 13-8 with a 2.43 ERA in 25 starts, striking out 196 batters to tie for eighth in the majors in the category. Ohtani is 2-0 with a 0.90 ERA in three starts in September, including a seven-inning scoreless stint against the Seattle Mariners on Saturday in which he allowed just three hits while striking out eight and walking one.

Ohtani at bat has been something this season as well, as he’s hitting .271 with 28 doubles, six triples, 34 home runs, 89 RBIs, and 85 runs scored. He hasn’t driven in a run in five games, so he’s due for a solid game at the plate.

Outfielder Mike Trout has been his usual outstanding self this season, hitting .273 with 21 doubles, two triples, 36 home runs, 73 RBIs, and 75 runs scored. He was 1-for-4 with a double, two RBIs, and a run scored in Thursday’s loss to the Texas Rangers.

Bottom Falling Out on Twins’ Postseason Chase

The Minnesota Twins are hoping for much better results as they return from the road for their final homestand of the season. Minnesota has dropped 17 of its last 20 road games as they have quickly fallen from the top spot in the AL Central to a distant third place with very little chance of catching up, especially after a three-game sweep by the fourth-place Kansas City Royals this week.

I mean, to be very frank about it, disappointing and about as low on the scale as you can imagine,” Twins manager Rocco Baldelli said after Thursday’s loss to the Royals. “The baserunners just weren’t there for us. The opportunities weren’t there.

Minnesota will have right-hander Louie Varland on the mound on Friday. Varland is 0-1 with a 5.23 ERA in his first two major league starts. On Saturday, he gave up four runs in five innings against the Cleveland Guardians.

Things haven’t been going well at the plate either, with Minnesota managing just two hits in Thursday’s loss. The Twins’ only run of the game was scored on a sacrifice fly by outfielder Nick Gordon.

Angels vs Twins Head-To-Head

The Los Angeles Angels have a 2-1 lead in the season series against the Minnesota Twins heading into this weekend. Los Angeles is trying for a second straight season series win after winning five of seven matchups in 2021.

The Angels were 3-1 at Target Field a season ago and have won two of their last three series played at the venue. As a result, the MLB lines for Friday’s contest favor the Angels to come away with the victory.

Angels vs Twins Game Information

  • Game: Angels (65-85) vs Twins (73-77)
  • Location: Target Field, Minnesota
  • Day/Time: Friday, Sept. 23rd, 8:10 p.m. ET
  • Angels vs Twins Live Stream: MLB.tv

Angels vs Twins Betting Lines

Team RunLine Moneyline Total Team Total
Los Angeles Angels

S. Ohtani -R

-1½ +115 -158 6½-120o 3½-140o


Minnesota Twins

L. Varland -R

+1½ -135 +143 6½Evu 2½-150o


Angels vs Twins Prediction

The Los Angeles Angels have a better pitcher and hotter offense than the Minnesota Twins. Those will lead them to the series-opening win.

When doing your MLB betting, take Los Angeles to win on the road.

Angels vs Twins Edge

Angels vs Twins Results

Angels vs Twins Game Injuries

Angels vs Twins Game Summary

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