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Bet On Brewers to Take Series Opener vs Cardinals

The teams at the top and bottom of the NL Central standings square off for the first time in 2024, as the Milwaukee Brewers begin a three-game weekend series against the host St. Louis Cardinals on Friday night. These two teams are long-time rivals, making this game one of the top MLB bets today.

Milwaukee comes into this series having dropped three of its last four contests and holding a slight half-game lead on the Chicago Cubs for the top spot in the division standings. St. Louis took two of three in its last series against the host Oakland Athletics but is still bringing up the rear in a division race that has all five teams within three games of each other.

Bet On Brewers to Take Series Opener vs Cardinals
Bet On Brewers to Take Series Opener vs Cardinals

The Brewers will send right-hander Freddy Peralta to the mound for the series opener. Peralta is 2-0 with a 2.55 ERA this season, striking out 26 in 17⅔ innings. He shut down the Baltimore Orioles in his last start, going six innings and allowing one run on five hits while striking out 11 last Friday.

St. Louis will have righty Kyle Gibson making his fourth start of the season on Friday. In his first season with the Cardinals, Gibson has struggled, allowing at least four runs in each of his last two starts. He took the loss against the Arizona Diamondbacks last Saturday after pitching six innings and giving up four runs on six hits while walking three.

Check the latest MLB Odds here!

Brewers vs Cardinals Game Information

  • Game: Brewers (11-6) vs Cardinals (9-10)
  • Date/Time: Friday, April 19, 8:15 p.m. ET
  • Location: Busch Stadium, St. Louis, MO
  • Brewers vs Cardinals Live Stream: MLB.tv


This is the first series of the season between these rivals, who will face each other a total of 13 times in 2024. Milwaukee won the season series between these clubs in 2023, going 8-5 against the Cardinals, including a 4-3 record in games played in St. Louis.

The Brewers are favored in the series opener, sitting at -112 on the moneyline compared to the Cardinals at +102. The MLB run lines put Milwaukee at +145 when giving 1½ runs, while St. Louis is -165 when getting those runs. The over/under is 7½ runs, with -110 odds on either side of the wager.

The first pitch for this contest is scheduled for 8:15 p.m. ET, and you can watch it live on MLB.TV.

Here’s a look at some MLB Lines and MLB Spreads to consider!

Brewers vs Cardinals Odds and Spreads


  • St. Louis is 11-8 ATS this season.
  • Milwaukee is 5-1 straight-up in its last six games vs the Cardinals.
  • The total has gone over in nine of the Brewers’ last 10 games.
  • St. Louis is 2-5 straight-up in its last seven games against a National League opponent.
  • Milwaukee is 9-3 straight-up in its last 12 games against an NL Central opponent.
  • The total has gone under in four of the Cardinals’ last five games.
  • The Brewers are 7-2 ATS on the road in 2024.
  • The over is 12-5 in Milwaukee’s 17 games this season.


Brewers vs Cardinals Over/Under Pick: Over 7½

Milwaukee has been able to hit the ball well this season, as shown by the team’s over/under record of 12-5, which always makes them a solid MLB bet for the over. The Brewers are ninth in the majors in runs with 98 while ranking second in baseball in team batting average at .277. St. Louis has been on the other end of the rankings, but the Cardinals playing at home are usually a stronger team.

Catcher William Contreras has been the most consistent player at the plate for the Brewers, ranking seventh in the majors with a .358 batting average. He has four doubles, four home runs and team highs of 16 runs scored and 17 RBI. He had a 12-game hitting streak snapped in Wednesday’s win over the San Diego Padres, so he’ll be looking to start a new string in this one.



Brewers vs Cardinals ATS Pick: Brewers -1½ (+145)

The Brewers should be one of your top MLB bets today, as they have Peralta on the mound and a division opponent to face. Milwaukee is looking to get back on the right track after dropping two of three to the Padres, and it should be able to do that against the Cardinals.

St. Louis will put up a good fight at home, but Gibson has really struggled this season and is facing one of the better-hitting teams in baseball. The rest of the series won’t be as easy to predict, but we really like Milwaukee to pick up the easy win in this one, so put your bet online on the visiting team.


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Brewers vs Cardinals PlayerProp Pick: Freddy Peralta Over 7½ Strikeouts (+120)

Peralta has been dealing on the mound this season, recording at least seven strikeouts in every game he’s started. He dominated the Orioles in his last start, with 11 of his 18 outs coming via the strikeout. St. Louis will likely be pressed to do well in front of the home crowd against the first-place team in the division, so taking Peralta to record at least eight strikeouts is one of the easier MLB picks today.



Brewers vs Cardinals Prediction

Brewers 8, Cardinals 2



Questions Of The Day

Have the Brewers and Cardinals played each other this season?

This will be the first time these NL Central rivals have faced each other in 2024.

Who won the season series between the Brewers and Cardinals in 2023?

Milwaukee won the season series 8-5, including a 4-3 record in games played in St. Louis.


The odds and predictions in the article are based on the time of writing and publication. They may differ as to when the actual event takes place.

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