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Brewers vs Reds Prediction, Game Preview, Live Stream, Odds & Picks, Sept. 22

NL Central Foes Begin Four-Game Series

Brewers Chasing Wild Card

Everybody loves a divisional rivalry, but with two teams heading in completely opposite directions, we do not have much of a rivalry. Nonetheless, the Milwaukee Brewers are traveling to Great American Ball Park to begin a four-game series against the Cincinnati Reds. Both teams are fresh off a win and it is time to bet on MLB.

With October looming closer, the Brewers are 79-70 and in second place in the National League Central.

Brewers vs Reds Prediction, Game Preview, Live Stream, Odds & Picks, Sept. 22
Brewers vs Reds Prediction, Game Preview, Live Stream, Odds & Picks, Sept. 22

They are 7½ games back of the division-leading St. Louis Cardinals and are desperately reaching for the final Wild Card spot. Milwaukee is 2½ games behind the Philadelphia Phillies, who just earned a huge walk-off win against the Toronto Blue Jays.

At the bottom half of the NL Central, we have the Cincinnati Reds. The Reds have not had the season they envisioned as they sit with a 59-90 record. At the trade deadline, they blew the team up and sit in fourth place in the worst division in the NL.

Let’s check the latest MLB picks, stats, injury reports, and  MLB odds for Brewers vs Reds. We’ve plenty of MLB predictions for you to consider.

Milwaukee Needs Wins

There are only 13 games remaining in the schedule for the Milwaukee Brewers, and they have to take advantage of this opportunity if they want to play baseball while every other team is watching on their couches. Both teams are fresh off wins, so who will you take in your MLB picks and parlays?

We are in store for a fun pitching matchup with Brandon Woodruff on the mound. The 29-year-old right-hander is 11-4 this season with a 3.26 ERA, 1.10 WHIP, and 162 strikeouts through 135.1 innings.

Woodruff has pitched in three games against the Cincinnati Reds in 2022 and has struggled. He has a 5.63 ERA against the Reds, who hit .270 against him. That is compared to their season average of .220.

Milwaukee, fresh out of the New York gauntlet, has not been very good at covering the spread this season. The Brewers are 62-86 this season, including 31-46 on the road.

Reds Turn to Greene

The Cincinnati Reds started the 2022 season as the worst team in baseball by far. That quickly changed and they are now a respectable team, especially in the world of betting. Words cannot describe their early-season struggles, but they are slightly better now.

Cincinnati will rely on Hunter Greene to take the mound tonight. The 23-year-old has been a very fun player to watch. He has a 4-12 record, 4.97 ERA, 1.26 WHIP, and 138 strikeouts through 108.2 innings. That puts two strikeout machines on the rubber.

Milwaukee has been one of many kryptonite for Greene. He has a 9.69 ERA against the Brew Crew in three games. Through 13.0 innings, he has given up 14 earned runs. This will be his second start since coming off the IL.

Covering is a lot easier than winning on the moneyline for the Reds. They are 71-76 against the spread but 31-41 at home. The MLB lines will be interesting, considering both pitchers struggle against the opposing team.

Brewers vs Reds Head-to-Head

If you are betting online, you will not be surprised to learn the Milwaukee Brewers have the head-to-head advantage in the season series. Milwaukee is 10-5 in 2022 against Cincinnati as they face off for their final series of the season.

Brewers vs Reds Game Information

  • Game: Brewers (79-70) vs Reds (59-90)
  • Location: Great American Ball Park, Cincinnati
  • Day/Time: Thursday, Sept. 22, 6:40 p.m. ET
  • Brewers vs Reds Live stream:  MLB.tv

Brewers vs Reds Betting Lines

Team Run Line Moneyline Total Team Total
Milwaukee Brewers
B. Woodruff -R
-1½ +105 -152 7½ -115o 4½ +105o
4½ -135u
Cincinnati Reds
H. Greene -R
+1½ -125 +137 7½ -105u 3½ +115o
3½ -145u

Brewers vs Reds Prediction

Greene is young and he is hungry. He has not allowed a run in his last two outings and will keep that momentum going for the Cincinnati Reds as they take on the Milwaukee Brewers. Although they are the underdogs on our sportsbook, take the Reds.

Green and the Reds have nothing to lose while the Brewers have a lot of pressure on them.

Brewers vs Reds Edge

Brewers vs Reds Results

Brewers vs Reds Game Injuries

Brewers vs Reds Game Summary

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