Cubs vs Padres Same Game Parlay Picks for April 15: Fade Imanaga (4.5) Strikeout Prop
- Padres moneyline odds (+128) are a solid value at home.
- Shota Imanaga’s 4.5 strikeout total is worth chasing.
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Cubs vs Padres SGP Picks Today, April 15, 2025

Top 4 Cubs vs Padres Parlay Picks
1. Padres ML +128
Don’t let the MLB lines fool you. San Diego is rolling and has a great chance to win at home on back-to-back nights against the Chicago Cubs. The Padres are 14-3 overall and a perfect 11-0 at home after clobbering the Cubs 10-4 on Monday. That win wasn’t a fluke, either: they matched Chicago in hits and crushed them in the late innings. With plus-money MLB same-game parlay odds and the Cubs bullpen imploding, this is a sharp value play.
2. Shōta Imanaga Under 4.5 Strikeouts (-143)
For anyone locking in MLB props today, Imanaga looks sharp with a 2.70 ERA and a stellar 0.90 WHIP, but the strikeout numbers haven’t followed. He’s averaging just 5.4 K/9 through 23.1 innings with only one swing-and-miss pitch working. He struck out just four Padres across 7.1 innings earlier this month — and San Diego still ranks No. 1 in strikeout avoidance. With a weak K upside and a tough matchup, this is one of Tuesday night’s smarter fade MLB picks.
Bet on Shōta Imanaga Under 4.5 Strikeouts (-143)
3. Over 7.5 Total Runs (-120)
The Cubs lead the league in runs (6.32), RBIs (6.16) and walks per game (4.53) while the Padres rank 8th in scoring (4.88) with the No. 2 team batting average (.284). Monday’s 10-4 Padres win saw 21 combined hits and both bullpens touched up. Given the Cubs’ No. 1 rank in run differential and the Padres’ offensive depth, the MLB odds on the over are too short. It’s a must-consider when making your MLB prop picks.
Bet on Cubs vs Padres Over 7.5 Total Runs (-120)
4. Fernando Tatis Jr. Over 1.5 Total Bases (+112)
Fernando Tatis Jr. is now batting .361 with a .429 OBP and a .672 slugging percentage, ranking among the league’s hottest hitters, per Cubs vs Padres stats. On Monday, he racked up two home runs and three RBIs against Cubs pitching, bringing his total to six HRs and 12 RBIs this season. He’s crushing it at the plate with 2+ hits in three of his last four games. With those numbers, this is one of the safest MLB parlay picks today.
HE DOES IT AGAIN 😤
Fernando Tatis Jr. is now tied for the Major League lead in home runs 🔥 pic.twitter.com/rm2pdENst0
— MLB (@MLB) April 15, 2025
Bet on Fernando Tatis Jr. Over 1.5 Total Bases (+112)
Cubs vs Padres How to Watch
- Game: Cubs (11-8) vs Padres (14-3)
- Date/Time: Tuesday, April 15, 9:40 p.m. ET
- Location: Petco Park, San Diego, CA
- Cubs vs Padres Live Stream: MLB.tv
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Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets