Dodgers vs Cubs MLB Same Game Parlay Picks March 19: Bet Ohtani to Deliver in LA Win

Baseball fans at Tokyo Dome had to be loving life as local heroes Yoshinobu Yamamoto and Shohei Ohtani stole the show in the first game of the 2025 Major League Baseball season. Baseball bettors need to get to work with the first pitch on Wednesday coming around 6:10 a.m. ET

Let’s check out some MLB parlay picks as the reigning World Series champion Los Angeles Dodgers look to sweep the two games in the Tokyo Series against the Chicago Cubs.

The Dodgers got their title defense going with a 4-1 win. Los Angeles is looking good in the MLB World Series odds board at +250 to repeat.

With MLB odds favoring the defending champs on Wednesday, we’re rolling with the Dodgers on the run line, hitting the over, taking an Ohtani prop and banking on an NRFI (No Run First Inning).

Dodgers vs Cubs How to Watch

• Game: Los Angeles Dodgers (1-0) vs Chicago Cubs (0-1)
• Date/Time: Wednesday, March 19, 6:00 a.m.
• Location: Tokyo Dome, Tokyo, Japan
• Dodgers vs Cubs Live Stream: Fubo TV

Find updated Dodgers vs Cubs MLB injuries here.

Dodgers vs Cubs Betting Trends

• The Cubs covered 43 in 78 games following a loss during the 2024 season.
• The Dodgers were just 51-57 on the run line following a win last season.
• Justin Steele allowed 17 hits and struck out 31 in the first inning in his 24 starts last season.
• Tokyo Dome’s limited MLB Park Factor data suggests a below-average run-scoring environment.

Cubs left-hander Justin Steele’s 4.13 ERA in the first inning is something to consider as he faces perhaps the best lineup in baseball. There was only one base runner in the first inning in Tuesday’s opener. NRFI at -124 is the right play here in the MLB picks.

Dodgers vs Cubs Free MLB Parlay Picks

• Leg 1. Los Angeles Dodgers -1.5 (+110)

It is hard to know what to expect from Roki Sasaki as the Game 2 starting pitcher for the Los Angeles Dodgers makes his MLB debut. He will make plenty of MLB news either way.

Roki Sasaki during World Baseball Classic play in Japan: 3.2 IP, 2 H, 1 R, 2 BB, 8 K

What will he do in his Dodger debut on Wednesday? #TokyoSeries pic.twitter.com/sOBZTu911n

— MLB (@MLB) March 15, 2025

Eight of the nine batters for the Dodgers reached base at least once in Tuesday’s 4-1 win even without Mookie Betts and Freddie Freeman in the lineup. Expect more of the same as the Tokyo Series wraps up.

The Dodgers scored three of their four runs in the fifth inning in the opener. It wasn’t due to a lack of opportunity as the Dodgers were 3-for-15 with runners in scoring position. If they get that many chances again, the Dodgers should cover the -1.5 run line.

Bet on Los Angeles Dodgers -1.5 (+110)

• Leg 2. Dodgers vs Cubs Over 8 Runs (-110)

There were just three extra-base hits and one stolen base as the Dodgers and Cubs opened the 2025 MLB season with a low-scoring affair.

The total is at 8 for the second game in a row. In Steele’s first five starts in 2024, an average of 11 runs were scored, per Dodgers vs Cubs stats. That is enough to go with this early-morning clash to finish over the total.

MLB hitters aren’t used to taking their cuts this early in the morning and that could have played a role in what happened in Tuesday’s opener. They should be more locked in now with the game landing over.

Bet on Dodgers vs Cubs Over 8 Runs (-110)

• Leg 3. Shohei Ohtani 1+ Hits in a Dodgers Win (+114)

This is Shohei Ohtani’s world and we are just living in it. Getting to play in Japan has to be extra special for the reigning National League Most Valuable Player.

Shohei Ohtani is just having fun out there 🤩 #TokyoSeries pic.twitter.com/W8SwkZXUiS

— MLB (@MLB) March 18, 2025

A heavy favorite in MLB futures odds (+185) to win back-to-back MVP awards, Ohtani had two hits in the opener and don’t be surprised to see that happen again.

Take the +114 odds for Ohtani to have at least one hit in a win by the Dodgers in your MLB parlay picks today. It might even be worth taking a look at the +304 odds for the Dodgers to win and Ohtani to have at least two hits.

Bet on Shohei Ohtani to have 1+ Hits in a Win by the Dodgers (+114)

• Leg 4. NRFI (-124)

The Dodgers did most of their damage when the Cubs went to their bullpen in the series opener. With Sasaki a bit of an unknown commodity, it is pretty tempting to go with -124 odds for no runs to be scored in the first inning.

Bet on No Score in First Inning (-124)

Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets.