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Home » MLB Betting » MLB Picks » Giants vs Padres Prediction, Preview, Stream, Odds & Picks, Oct, 4.

Giants vs Padres Prediction, Preview, Stream, Odds & Picks, Oct, 4.

Matt De Saro by Matt De Saro
Oct 4, 2022, 1:30pm ET
in MLB Picks
Giants vs Padres Prediction, Preview, Stream, Odds & Picks, Oct, 4.

Giants vs Padres Prediction, Preview, Stream, Odds & Picks, Oct, 4.

San Diego’s Seeding

The San Diego Padres are already in the playoffs, but still, have something at stake when they host the San Francisco Giants Tuesday night.

The Padres (88-72) still have to fend off the Philadelphia Phillies to retain the No. 5 seed. If the season ended today, San Diego plays the (presumptive) fourth-seeded New York Mets. If the Padres end as the No. 6 seed, they will have to face the third-seeded St. Louis Cardinals.

The San Francisco Giants (80-80) are just trying to get to the positive side of break-even this season. The Padres won the series opener, 7-4, in a game that was scoreless going to the bottom of the eighth inning.

Let’s check the latest MLB odds, stats, injury reports, and MLB lines for Giants vs Padres. We’ve plenty of Vegas MLB odds for you to consider.

Giants’ Coin-Flip Season

Monday’s loss left the San Francisco Giants at a “perfect” 80-80 this season, in danger of a losing season just one year after leading MLB in wins. The Giants enter Tuesday with a 10-3 record in their last 13, They’ve lost their six games against the Padres however.

Lefty Carlos Rodon (14-8, 2.88 ERA) gets the Giants’ start Tuesday night. Rodon blanked the Colorado Rockies over six innings in his last start (two hits, 10 strikeouts, no walks). Rodon is ranked third in strikeouts with 237, fanning in double figures five times in his last eight outings.

Manaea’s Not the Man

If there is one thing lefthander Sean Manaea (7-9, 5.15 ERA) needs right now, it’s a turn of fortune. He’s been one of the worst starters among playoff-bound teams this season, with 7.00 ERA in his last five starts. The Padres are fighting to hold the second wild-card spot. He’s not helping.

Manaea’s poor numbers against the Giants this season include a 4.76 ERA in three starts (nine earned runs in 17 innings). Manaea is just 1-4 in his previous 10 games.

It is conceivable that the Friars lose the No. 5 seed and then be stuck with a more challenging opponent to begin the postseason.

Giants vs Padres Head-to-Head

The Padres hold a 12-5 advantage against the Giants this season.

Giants vs Padres Game Information

  • Game: Giants (80-80) vs Padres (88-72)
  • Location: Petco Park, San Diego, CA
  • Day/Time: Tuesday, Oct. 4th, 9:40 p.m. ET
  • Giants vs Padres Live stream: MLB.tv

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Giants vs Padres Betting Lines

Team Run Line Moneyline Total Team Total
San Francisco Giants

C. Rodon -L

+1½ -175 +129 7 -120o 3½ +115o

3½ -145u

San Diego Padres

S. Manaea -L

-1½ +155 -144 7 Evu 3½ -130o

3½ Evu

The odds in this chart are based on the time of publication. They are subject to change.

Parlay & Odds Calculator

Giants vs Padres Prediction

The Padres have more at stake, but lack the skill on the hill to get it done. Lefty Rodon is one of the better pitchers in the league, while Manaea isn’t producing. Expect the Giants’ lefty to be on top of his game in his last start of the season.

BET THIS PICK: San Francisco Giants (+129)

“The odds and predictions in the article are based on time of writing and publication. They may differ as to when the actual event takes place.”

Giants vs Padres Trends

Giants vs Padres Edge

Giants vs Padres Results

Giants vs Padres Game Injuries

Giants vs Padres Game Summary

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Tags: MLBSan Diego PadresSan Francisco Giants
Matt De Saro

Matt De Saro

Matthew De Saro is a writer and media personality covering sports betting online since 2016. He grew up in New Jersey as a die-hard fan of NY sports and has made a career of his passion for competition. Matthew specializes in the MLB, NFL, and NBA but has covered everything from the Super Bowl to the Puppy Bowl.

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