MLB Home Run Props and Picks for Friday, June 20: De La Cruz a Home Run Pick in St. Louis

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- Houston’s Yainer Diaz offers long odds (+500) that we like in our MLB home run props.
- Consider a blast by Colorado’s Ryan McMahon at +350.
Top 3 Home Run Prop Picks for June 20
1. Elly De La Cruz Home Run (+480) Reds vs Cardinals 7:15 p.m. ET
Since his run of four straight games with a home run, De La Cruz is 0-for-10 over a three-game stretch. That reverses course tonight in St. Louis, where he faces Andre Pallante. The right-hander has seen his home run rate soar this year and while most of it has happened on the road, he’s susceptible to the long ball right now. De La Cruz already has 16 and the MLB odds look right for a pick here.
Bet on Elly De La Cruz to Hit A Home Run (+)
FOUR straight games with a home run for Elly De La Cruz 🤯 pic.twitter.com/SfGwXfLYN4
— MLB (@MLB) June 15, 2025
2. Yainer Diaz Home Run (+470) Astros vs Angels 9:38 p.m. ET
The Astros’ home run binge was interrupted Thursday in Sacramento, but they’ve been on a tear otherwise. They had eight in the previous two games against the A’s and while Diaz was on the outside looking into that party, he has been heating up. He also has a double in two career at-bats against Yusei Kikuchi and has been very good against lefties this year. This one works for our MLB props today.
Bet on Yainer Diaz to Hit a Home Run (+470)
Yainer Diaz walks it off in Houston! 👏
(via @MLB)pic.twitter.com/eZTi2Tkvgj
— FOX Sports: MLB (@MLBONFOX) May 31, 2025
3. Ryan McMahon Home Run (+480) Diamondbacks vs Rockies 8:40 p.m. ET
We don’t get to jump on too many Rockies with our MLB betting trends, but here’s a stab at it. This is a Coors Field contest, so there’s that, and McMahon will be taking aim at struggling Zac Gallen. The righty has allowed five homers over his last three starts and served up four against the Rockies earlier in the year.
We also isolated this in our MLB matchups because McMahon is a .282 lifetime hitter vs Gallen.
Bet on Ryan McMahon to Hit A Home Run (+480)
That one isn’t coming back.
Ryan McMahon CRUSHES a 441-foot homer. pic.twitter.com/fA9uz6No8Q
— MLB (@MLB) June 13, 2025
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MLB Props FAQs
What items in MLB news today might impact wagering?
Royals rookie Jac Caglianone hit his first blast, with many more to come.
Who leads the majors in home runs in the ninth inning?
A’s rookie Nick Kurtz has an MLB-high.
Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets