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Padres vs Mariners Prediction, Game Preview, Live Stream, Odds & Picks, Sept. 14

Both Teams Chasing Wild Cards

Interleague Series Concludes

With the madness of September baseball, where we see a lot of pivotal rivalries within their own division, we have an interleague matchup on Wednesday afternoon to give you a break from that. The San Diego Padres will take on the Seattle Mariners at T-Mobile Park in the finale of the two-game series.

Even though this is just a two-game series, the MLB playoff odds will be greatly impacted by these two games. With just over 20 games remaining, every single pitch matters.

Padres vs Mariners Prediction, Game Preview, Live Stream, Odds & Picks, Sept. 14
Padres vs Mariners Prediction, Game Preview, Live Stream, Odds & Picks, Sept. 14

The Padres enter the game with a 78-64 record, well behind the Los Angeles Dodgers, who have the best record in MLB. They have a two-game lead over the Milwaukee Brewers for the third Wild Card spot in the NL.

Seattle looks to finally end a 20-year playoff drought. The Mariners hold a 79-62 record in the American League West. They are in a similar spot as the Padres, as they are both trailing the winningest team in their league. The Mariners are tied with Tampa Bay for the second Wild Card in the AL.

Let’s check the latest MLB picks, stats, injury reports, and MLB odds for the Padres vs Mariners. We’ve plenty of MLB predictions for you to consider.

Clock Ticking on Padres

As the season quickly winds down, the San Diego Padres are running out of time to figure things out. San Diego continues to be included in MLB picks and parlays, but often for people betting against them as the Padres try to gain chemistry.

Mike Clevinger will start for San Diego. The long-haired wonder has struggled with a 5-6 record, 4.13 ERA, 1.19 WHIP and 81 strikeouts. Opponents hit .231 against him on the road, where he has a 4.55 ERA.

Clevinger has thrown six innings this season against Seattle, allowing four earned runs. He has allowed nine earned runs in his last two starts on the bump.

San Diego has struggled very much against the spread in 2022. The Padres are 61-80 ATS but an impressive 38-34 on the road. Look for a lot of runs from their potent offense.

Mariners on Playoff Path

Nothing is set in stone, but the Seattle Mariners really appear to be playoff bound. They are often among the favorites in the MLB lines, and for good reason. Seattle is one of the hottest teams in baseball with a 7-3 record in its last 10 outings.

Luis Castillo will take the mound with the fifth-best ERA in MLB. The 29-year-old is 6-5 with a 2.81 ERA, 1.07 WHIP and 141 strikeouts. Opponents hit just .200 against Castillo at home, but the Mariners have won just one of their last four games when he was on the mound.

Seattle dominates the moneyline and the spread alike. They are 76-64 against the spread, which is very impressive for a team that is usually favored. A lot of that has to do with their very underrated pitching staff. Their over/under at home this season is 28-39-3.

Padres vs Mariners Head-to-Head

When betting online, you should note that the Mariners are 2-1 against the Padres after Tuesday’s 2-0 loss. The Padres have been outscored 14-6.

Padres vs Mariners Game Information

  • Game: Padres (78-64) vs Mariners (79-62)
  • Location: T-Mobile Park, Seattle
  • Day/Time: Wednesday, Sept. 14, 4:10 p.m. ET
  • Padres vs Mariners Live stream: MLB.tv

Padres vs Mariners Betting Lines

Team Handicap Moneyline Total Team Total
San Diego Padres
M. Clevinger -R
+1½ -160 +138 7½Evo 3½ +105o
3½ -135u
Seattle Mariners
L. Castillo -R
-1½ +140 -153 7½-120u 3½ -150o
3½ +120u

Padres vs Mariners Prediction

The San Diego Padres and the Seattle Mariners are evenly matched, but there is one team that has the upper hand. Seattle has the better pitcher with Luis Castillo on the mound, and you should take the Mariners.

Our sportsbook has the Mariners as the favorites, and with good reason. Take them on the moneyline.

The odds and predictions in the article are based on the time of writing and publication. They may differ as to when the actual event takes place.

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