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Phillies vs Cardinals Prediction, Game Preview, Live Stream, Odds, Picks, Oct. 07

Best-of-3 Under the Arch

Redbirds’ Annual Postseason Participant

The St. Louis Cardinals open their quest for a 12th World Series title, hosting the Philadelphia Phillies in Game 1 of a National League wild-card series Friday afternoon. Winners of the National League Central Division title, it’s the fourth consecutive postseason appearance by the Cards. Philadelphia’s in the playoffs for the first time since 2011, that after “earning” the

NL’s final spot.

Phillies vs Cardinals Prediction, Game Preview, Live Stream, Odds, Picks, Oct. 07
Phillies vs Cardinals Prediction, Game Preview, Live Stream, Odds, Picks, Oct. 07

Check our in-depth preview of Game 1 to help you with your betting online.

Let’s check the latest MLB odds, stats, injury reports and MLB lines for Phillies vs Cardinals. We’ve plenty of MLB Vegas odds for you to consider.

Phillies Not Exactly Rolling

The Philadelphia Phillies accomplished the feat of making the postseason-first time since 2011- but not before trying to give away the invitation. Philly lost 13 of its final 20, leaving the door ajar. However, the Milwaukee Brewers couldn’t stand the hospitality, thus imploding themselves (4-6 in last 10) when it counted.

Righthander Zack Wheeler gets the series-opening start. Wheeler was 12-7 this season with a 2.82 ERA in 26 starts/appearances, 163 strikeouts in 153 innings. He opposed the Cardinals twice during the season, 2-0 with a can’t-do-better 0.00 ERA (14 innings, nine hits while, 10 strikeouts, two walks).

Outfielder Kyle Schwarber led the Phillies with 46 home runs and 94 RBIs, and there’s postseason experience from his time with the Chicago Cubs and Boston Red Sox. Schwarber hit .218 this past season, 21 doubles, three triples and 100 runs scored.

Outfielder Bryce Harper can get hot and carry a team. Harper hasn’t been in the playoffs since 2017 (Washington Nationals), and hasn’t come through with a big performance in the postseason thus far. Harper, missing some time with a broken thumb, hit .286 with 28 doubles, a triple, 18 homers, 65 RBIs and 63 runs scored in 99 games.

Cardinals Ending An Era, But How?

The St. Louis Cardinals have had some great postseason runs with Albert Pujols, Yadier Molina and Adam Wainwright on their roster, winning the titles in both 2006 and 2011. With two sure-fire Hall-of-Famers in Pujols and Molina set to retire after this season (Wainwright is undecided), the team would love nothing more than to send them out with a trophy.

“We competed well for 162 (games),” manager Ollie Marmol said after Wednesday’s regular-season finale against the Pittsburgh Pirates. “Now, the fun begins. We are ready to go.”

Pujols has been hot at the plate of late, nine homers since the start of September. It will be first baseman Paul Goldschmidt who needs to be hot as well if the Cardinals are to make a run. The NL MVP candidate (favorite?) batted .317 (third in MLB), driving in the 115 runs (fourth in MLB) and T8 with 35 home runs.

Then, there’s All-Star third baseman Nolan Arenado. He hit .293, with 42 doubles, a triple, 30 home runs, 103 RBIs and 73 runs scored. However, just .160 (one homer) in three playoff appearances with the Cardinals and the Colorado Rockies.

Lefty Jose Quintana has the Cards’ opening-game assignment. Quintana was 3-2 with a 2.01 ERA in 12 starts after arriving via deadline trade with the Pittsburgh Pirates. He did draw the Philadelphia Phillies once this season (with Pittsburgh), throwing 5⅔ scoreless innings (four hits, four strikeouts, two walks).

Phillies vs Cardinals Game Injuries

Phillies vs Cardinals Head-To-Head

The Philadelphia Phillies took the season series with the St. Louis Cardinals, 4-3. That’s not news, since the Phillies won the last four season series they’ve played (they didn’t in 2020).

Philly is 8-7 at Busch since the start of the 2018 campaign. The MLB lines for Friday’s Game 1 give the slightest of edges to the Cardinals to earn the victory.

Phillies vs Cardinals Game Information

  • Game: Phillies (87-75) vs Cardinals (93-69)
  • Location: Busch Stadium, St. Louis, MO
  • Day/Time: Friday, Oct. 7th, 2:07 p.m. ET
  • Phillies vs Cardinals Live Stream: MLB.tv

Phillies vs Cardinals Betting Lines

Team Handicap Moneyline Total Team Total
Philadelphia Phillies

Z. Wheeler -R

+1½ -225 -102 6½-120o 3½Evo


St. Louis Cardinals

J. Quintana -L

-1½ +185 -108 6½Evu 3½-105o


The odds in this chart are based on the time of publication. They are subject to change.

Phillies vs Cardinals Prediction

The St. Louis Cardinals have been the better team all season long, and they have much more playoff experience than do the Phillies. It won’t be easy, but the Cardinals should take care of the Phillies and open the series with a win.

When making your MLB picks, take St. Louis Friday afternoon at home.

Phillies vs Cardinals Edge

Phillies vs Cardinals Results

Phillies vs Cardinals Game Summary

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