Phillies vs Rockies Prediction, MLB Prop Bets and Parlay Picks Wednesday, 5/21

Oscar Diaz

· May 21 - 3 minutes read

Phillies

Rockies

-205

Moneyline

+178

-1½ -150

Run Line

+1½ +130

O 11 ½ +105

Total Game

U 11½ -125

O 6 ½ -122 U 6½ -108

Team Total

O 4½ -115 U 4½ -115

Place your Bets on Phillies vs Rockies at BetUS Sportsbook!

Phillies vs Rockies Prediction, MLB Prop Bets and Parlay Picks Wednesday, 5/21 — Kyle Schwarber #12 of the Philadelphia Phillies| Nick Cammett/Getty Images/AFP

Make bank with our 2025 MLB Season picks! Join with our promo code HUDDLE125.
Philadelphia on the -1.5 Run Line is our best bet.
Bet Kyle Schwarber Over 1.5 Total Bases.

Phillies vs Rockies Prediction and Best Bets Today, May 21

My prediction

Run Line Pick: Phillies -1.5

The Rockies are 3-25 in night games and have been outscored by 153 runs this season. That’s not a typo. That record leaves us without a real MLB moneyline pickas the juice just isn’t worth the squeeze. Taijuan Walker isn’t dominant, but he doesn’t have to be against a team hitting .217. Colorado’s bullpen has a 5.94 ERA, so even if Palmquist survives the first 4 innings, Philly’s deep lineup will eventually break through. For MLB same game parlay value, this is your safest anchor.

Bet on Phillies (-1.5)

Over/Under Pick: Over 11.5 (-105)

Normally, I’d hesitate on a number this high, but it’s Coors Field with the worst pitching staff in baseball on one side. The Phillies just put up 7 and 9 runs the last two nights, and they’re slugging .411 as a team. The Rockies? Their bullpen WHIP is 1.62, and opponents hit .301 off them. For MLB props today, targeting the Over is a logical fit alongside Philly stacks.

Bet on Over 11.5 Runs (-105)

Get More MLB Game Picks, Expert Analysis and Best Bets

My Best Prop Bets

Kyle Schwarber Over 1.5 Total Bases (-104)

Kyle Schwarber already has 17 home runs and is slugging .583. He’s cleared this prop in 4 of his last 6 and now faces a lefty who gave up 6 hits in 4 innings in his only start. The matchup plus ballpark plus Schwarber’s form? That’s a combo I’m backing every time. He’s the best play in MLB expert picks today for offensive props.

Bet on Kyle Schwarber Over 1.5 Total Bases (-104)

Phillies Race to 6 Runs (-150)

Philly has scored 6+ in four of its last five and faces a Rockies squad allowing a league-worst 6.5 runs per game. With Trea Turner setting the table and Bryce Harper, Nick Castellanos and Schwarber driving them in, this one shouldn’t take long to hit. This is one of my favorite MLB expert picks and parlays props on the board.

Bet on Phillies Race to 6 Runs (-150)