Red Sox vs Guardians Same Game Parlay Picks, Friday, 4/25

Red Sox vs Guardians SGP Picks Today, April 25, 2025
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The Cleveland Guardians have scored just two runs in Ben Lively’s first two home starts of the season. Will those who bet on MLB trust that trend will continue with the Boston Red Sox coming to town for the start of a weekend series?
The MLB odds have Cleveland at -102 to improve to 8-2 at home. Boston comes in at -105 on the moneyline.
There are some MLB parlay best bets today to consider when these two American League title contenders get together. There is a 60% chance of rain around the time of the first pitch.
Top 3 Red Sox vs Guardians Parlay Picks
1. Boston Moneyline (-105)
Cleveland has won four of its last five home games against the Red Sox. However, I like Rafael Devers, Alex Bregman, Trevor Story and the Red Sox to deliver on the road in the series opener in one of the MLB game predictions.
Boston has scored 28 more runs than the Guardians this season. Boston has 35 extra-base hits and 15 stolen bases in 13 road games. Keep that in mind when considering MLB parlay picks today.
2. Kristian Campbell to have 2+ Total Bases (+129)
Boston rookie Kristian Campbell has made himself at home on the road with a .349 batting average with seven of his 15 hits going for extra bases.
Kristian Campbell has reached safely in 21 of 22 games to start his career 👏 pic.twitter.com/FZDtPMlkN7
— MLB (@MLB) April 21, 2025
He is 0-for-8 with six strikeouts in his last two games. However, he already has four multi-hit games on the road this season.
Take a look at the +129 odds for Campbell to have 2+ total bases from hits when making MLB prop picks today.
Bet on Kristian Campbell to have 2+ Total Bases (+129)
3. Steven Kwan 1+ Runs + RBIs (-117)
Steven Kwan was 7-for-12 with three runs in the recent three-game series against the New York Yankees to raise his home batting average to .324.
Steven Kwan 👀📈 pic.twitter.com/bzUuCDgjEG
— MLB Network (@MLBNetwork) April 24, 2025
Take a look at the -117 odds for Kwan to have 1+ runs + RBIs in the series opener when making the MLB picks.
Bet on Steven Kwan to have 1+ Runs + RBIs (-117)
Red Sox vs Guardians How to Watch
- Game: Red Sox (14-13) vs Guardians (14-10)
- Date/Time: Friday, April 25, 7:10 p.m. ET
- Location: Progressive Field, Cleveland, OH
- Red Sox vs Guardians Live Stream: MLB.TV
Click here for Red Sox vs Guardian stats.
Odds and information are accurate at the time of writing. Please check with official sources for the latest updates before placing any bets