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Picks, Prediction for Reds vs Cubs on Saturday, May 27

The Chicago Cubs have a tough road toward evening up their series due to a major mismatch on the mound. The Cubs are slowly falling apart, with 9 losses in their last 12 games and four wins at home in May. The Reds are 3-6 in their last nine and fighting to avoid falling into last place in the NL Central.

The MLB odds list the Reds as heavy favorites despite a starting pitcher with an ERA above 8.00.

Reds vs Cubs Prediction, Game Preview, Live Stream, Odds and Picks May 27

Reds Dominate Series Opener

The Reds don’t often have much to celebrate, but Friday’s victory in the series opener was an exception. It was the third win in a row against the MLB spread and set them up for a repeat performance.

With a win, the Reds would leapfrog the Cubs and, depending on what the Cardinals do, could land in third place behind the Pirates.

Cubs Off Back-to-Back Losses

The Cubbies are in a 3-7 rut and one loss away from falling into last place in the NL Central on Saturday.

From an MLB betting standpoint, the Cubs are a winning team at home with a 14-12 record against the spread. In their last ten games, Chicago is 6-4 ATS with a return on investment of 32.89%.

Starting Pitchers

Brandon Williamson (0-0, 3.60) vs. Jameson Taillon (0-3, 8.10)

Brandon Williamson steps up to make his third career start for the Reds, hoping to bounce back after a rough second appearance. Williamson allowed four runs and four walks in 4⅓ innings to the St. Louis Cardinals on Monday, though the Reds eked out a win in extra innings. The rookie could have another tough game ahead as the Cubs rake vs. LHP with a .281 BA and .815 OPS.

Conversely, Jameson Taillon has been a total mess for the Cubbies. Chicago hasn’t won one of his seven starts, and Taillon’s ERA in May is up to 12.08. I’m wondering why he hasn’t yet been sent down in favor of any number of young arms the Cubs have in their farm system. He’s allowed twice as many hits as innings pitched in May and is not a guy to trust with your MLB picks.

Reds vs Cubs Head-to Head

The Reds own a 2-1 season series lead after Friday’st win and are 2-1 against the spread as underdogs on the MLB lines. Including last season, the Cubs are 13-9 against the spread. The Over/Under in that span is 12-6-3, including four straight OVER wins.

Reds vs Cubs Game Information

  • Game: Reds (22-29) vs Cubs (22-28)
  • Location: Wrigley Field, Chicago, IL
  • Day/Time: Saturday, May 27, 7:15 p.m. ET
  • Reds vs Cubs Live Stream: MLB.tv

Reds vs Cubs Betting Lines

Over/Under Pick

With Taillon on the bump, I think there is a good shot this game soars over the betting total on Saturday. Even if he holds it together, the Cubs have one of the highest bullpen ERAs in the MLB at 4.52 and could collapse at any moment.

Pick: Over 9 (-115)

Moneyline Pick

Both teams are below-average and struggling to remain relevant in the NL Central, but only one has a pitcher starting who belongs in Triple-A. Taillon has been a total mess, and I don’t believe he will suddenly turn it around on Saturday.

Pick: Cincinnati Reds +150

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