- AL Central Division Champs on Two-Game Win Streak
- Royals Tamed by Tigers
- Guardians Close the Sale
- Royals vs Guardians Head-To-Head
- Royals vs Guardians Game Information
- Royals vs Guardians Betting Lines
- Royals vs Guardians Prediction
- Royals vs Guardians Trends
- Royals vs Guardians Edge
- Royals vs Guardians Results
- Royals vs Guardians Game Injuries
- Royals vs Guardians Game Summary
Royals vs Guardians Prediction, Game Preview, Live Stream, Odds, Picks, Sept. 30
Guardians Close Regular Season with Visiting Royals
AL Central Division Champs on Two-Game Win Streak
The Cleveland Guardians go after a third straight win when they host the Kansas City Royals in the first of a six-game (that’s not a misprint), season-ending series between division Friday night. Cleveland took the final two games of its series with the Tampa Bay Rays, and has already clinched the AL Central title, 11 games ahead of the Chicago White Sox. Kansas City has lost three in a row, remaining bottom-feeders in the division.
Before you bet online, read our in-depth preview of the contest.

Let’s check the latest MLB odds, stats, injury reports, and MLB lines for Royals vs Guardians. We’ve plenty of Vegas MLB odds for you to consider.
Royals Tamed by Tigers
After winning five-of-six games against the Minnesota Twins and Seattle Mariners, the Kansas City Royals just didn’t have it against the Detroit Tigers, getting swept in a three-game set. Two of those games were one-run decisions, including a 10-inning loss in the opener.
Righthander Brady Singer tries to get the Royals back to their winning ways in his 24th start (27th appearance) Friday night. Singer is a solid 10-4 with a 2.99 ERA, 144 strikeouts in 147.2 innings. He’s been red-hot this month, 3-1 with a 1.38 ERA in four September starts. Singer is coming off a seven-inning stint against the Mariners last Friday (one run, five hits, eight strikeouts, two walks).
Shortstop Bobby Witt Jr. continues to make his case for American League Rookie of the Year, entering this elongated series on an 11-game hitting streak. The 22-year-old is batting .256 with 31 doubles, six triples, 20 home runs, 80 RBIs and 81 runs scored.
Guardians Close the Sale
The Cleveland Guardians have been one of the tougher teams to put away late in games this season. That was the case again Thursday, rallying to earn a 2-1 victory against a Tampa Bay Rays’ team needing that win to clinch a playoff spot. Cleveland scored a pair of runs in the eighth to spoil the Rays’ party in what could be a postseason preview.
“Kind of been our M.O. all year long,” pitcher Cal Quantrill said after Thursday’s win. “You can’t put us away. I don’t think we’re a very fun team to face.”
Rookie outfielder Steven Kwan drove in one of the runs with a double. Kwan is batting .302 (12th in baseball), 9-of-18 over his last four. He has 23 doubles, seven triples, six homers, 51 RBIs and 87 runs scored.
Righty Aaron Civale will get the start for the Guardians Friday night. Civale is 3-6 with a 5.19 ERA in 18 starts this season, striking out 84 over 85 innings. He was the winner in his last outing (against the Texas Rangers last Sunday), having surrendered two runs (three hits) over five innings. He struck out seven with no walks.
Royals vs Guardians Head-To-Head
Cleveland has an 8-5 advantage entering this long, season-ending series.The Guardians have won or tied the series with the Royals in six straight seasons prior to 2022. The MLB lines for Friday’s series opener are giving Cleveland a slight edge to open with a win.
Royals vs Guardians Game Information
- Game: Royals (63-93) vs Guardians (88-68)
- Location: Progressive Field, Cleveland, OH
- Day/Time: Friday, Sept, 30th, 7:10 p.m. ET
- Royals vs Guardians Live Stream: MLB.tv
Royals vs Guardians Betting Lines
Team | Handicap | Moneyline | Total | Team Total |
Kansas City Royals
B. Singer -R |
+1½ -190 | +124 | 7-105o | 3½+115o
3½-145u |
Cleveland Guardians
A. Civale -R |
-1½ +160 | -134 | 7-115u | 3½-115o
3½-115u |
The odds in this chart are based on the time of publication. They are subject to change.
Royals vs Guardians Prediction
The Kansas City Royals are slumping a bit, but they’ll have an ace in Singer on the mound. Regardless, Cleveland should come away with a win as they build toward the playoffs.
When doing your MLB betting, take Cleveland to get the home win.