76ers vs Clippers Game Preview, Live Stream, Odds, Picks & Predictions
Philadelphia Owns Loftier Ambitions
Teams Heading in Opposite Directions
The Philadelphia 76ers and Los Angeles Clippers are heading in opposite directions. The Philadelphia Sixers are riding a two-game winning streak into Friday’s showdown with the Los Angeles Clippers at Crytpo.com Arena. The Clippers, by contrast, are riding a four-game losing streak and desperate to get back on track.
Predictably, the NBA odds are cornered with the Sixers across all the markets. They’re the firm favorites to win straight up and they’re laying a whopping 5½ points to the hosts in the point spread betting markets. Will the Sixers come through on both scores?

Find out as we preview this matchup, weigh in on the odds and serve up choice NBA picks to spot.
Let’s check the latest news, stats, injury reports, and NBA odds for 76ers vs Clippers. We’ve plenty of predictions for you to consider.
Sixers Seek Third Straight Win
With the Boston Celtics on their case, the Philadelphia 76ers will be looking to clinch their third straight win and advance their bid for the Atlantic Division title. The Sixers are 45-27 and currently nudging ever so slightly ahead of the Celtics in the division standings.
The Sixers are also merely 1.5 games back of the Eastern Conference leaders, the Miami Heat (47-26) – a position they share with the Celtics – and a half-game behind the Milwaukee Bucks.
Most recently, the Sixers edged the Los Angeles Lakers 126-121 on the road. The Sixers closed as the massive 10-point road favorites, but failed to come through on the betting online odds despite taking the crucial win. It marked their second straight win after upsetting the Miami Heat 113-106 as the eight-point underdogs.
30 PTS | 10 REB | 3 BLK@JoelEmbiid was doing his thing last night in LA.
🎥 presented by @PALottery pic.twitter.com/SWJn10qo15
— Philadelphia 76ers (@sixers) March 24, 2022
Philadelphia is 35-36-1 against the spread (ATS) with a 2.0 winning margin on average and a -0.9 differential versus the spread. On the road, the Sixers are 20-14-1 ATS with a 2.0 winning margin on average and a +1.2 differential versus the spread.
Clippers Look to Keep Playoff Hopes Alive
The wheels have well and truly come undone for the Los Angeles Clippers in recent weeks. They’re riding a four-game losing streak and find themselves in very real danger of seeing their season fall to the wayside as they slipped to a subpar 3-7 mark in their last 10 games.
The Clippers are currently ranked eighth in the Western Conference standings, which would be good enough for a play-in spot if the season were to end today. Should they continue to leak more points down the stretch, though, who knows if they’ll even make the play-in cut at all.
Three of their losses have come on the road, including a 127-115 loss to the Denver Nuggets. In their last four home games, the Clippers are 2-2 straight up (SU) and 0-4 ATS. Most recently, they lost to the Toronto Raptors 103-100 at the Crypto.com Arena.
📊 14 PTS | 66.7% FG | 66.7% 3FG | 3 REB@Holla_At_Rob33 was locked in. pic.twitter.com/fYMmTygDmw
— LA Clippers (@LAClippers) March 23, 2022
On the season, the Clippers are 36-38 SU and 35-38-1 ATS with a 1.4 losing margin on average and -1.0 differential versus the spread. At home, the Clippers are 20-15 SU and 16-19-0 ATS with a 0.8 winning margin on average and -2.2 differential versus the spread.
76ers vs Clippers Head-to-Head
The Philadelphia 76ers have the 6-4 edge over the LA Clippers in the last 10 contests – a run that includes a 7-3-0 ATS record. The under has cashed in seven of these last 10 games.
The Clippers, however, own the most recent meeting after beating the 76ers 102-101 on the road on Jan. 21. The win represented an upset bv Los Angeles, with the Clippers closing as the 7½ -point road underdogs at the sportsbook exchange.
76ers vs Clippers Game Information
- Game: Philadelphia 76ers (45-27) vs LA Clippers (36-38)
- Location: Crypto.com Arena, Los Angeles
- Day/Time: Friday, 10:40 p.m. ET
- Live stream: NBA Game Pass
76ers vs Clippers Betting Lines
76ers vs Clippers Prediction
The Philadelphia 76ers are in a three-way battle with the Boston Celtics and the Milwaukee Bucks for second place in the Eastern Conference standings.
So, the Sixers are technically not only in the race for the Atlantic Division title, but they could challenge for top spot in the East. This kind of an incentive is hard to overlook. Add to that Philadelphia’s solid form, which is comprised of a 6-4 record in their last 10 games and a 4-1 record in their last five, against the Clippers’ four-game losing streak, and a strong case exists for the Sixers to win at the expense of Los Angeles.
Covering the 5½-point spread might be trickier for the Sixers, especially as the hosts will be keen to get back on trac at home. That said, the last two games did see the Clippers whimper to double-digit defeats, albeit on the road. Nevertheless, such defeats can have a ripple effect and knock back confidence.
