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76ers vs Lakers Prediction, Odds and Picks Friday, March 22

The betting odds show the Los Angeles Lakers as -7½ favorites over the Philadelphia 76ers as the undermanned contenders meet in L.A. Philadelphia has struggled mightily since losing MVP center Joel Embiid. But Los Angeles has not fared much better, especially when playing Philly. Led by Tyrese Maxey, who we like on the NBA player props, the 76ers could deliver as underdogs.


76ers vs Lakers Prediction, Odds and Picks Friday, March 22
76ers vs Lakers Prediction, Odds

76ers vs Lakers Game Information

  • Game: 76ers (38-31) vs Lakers (37-32)
  • Start time: 10:30 p.m. ET
  • Day Game: March 22
  • Location: Crypto.com Arena, Los Angeles
  • 76ers vs Lakers Live Stream: NBA Game Pass


Philadelphia is +7½ on the NBA point spreads and +256 on the moneyline. We’re not brave enough to recommend the latter, but we will take the points for Philly, especially since it has won seven straight games against the Lakers. Los Angeles is also 6-7 ATS when hosting Eastern Conference opponents. The total is set at 224 points given these teams’ injuries.


76ers vs Lakers Head-to-Head


76ers vs Lakers Odds and Spreads



  • The 76ers are 8-3 ATS in their last 11 matchups against the Lakers.
  • The Lakers are 2-6 ATS in their last eight games against Atlantic Division opponents.
  • Philadelphia is 9-3-1 ATS in its last 13 games played on a Friday.
  • Los Angeles is 2-3 ATS in its last five games with a line of -8 or shorter.
  • The total has gone over in nine of the Lakers’ last 11 games played in March.
  • The over is 7-1-0 in the Lakers’ last eight games when the total is in the 220s.
  • The total has gone over in 11 of Philadelphia’s last 20 games when facing a Western Conference opponent.
  • 76ers G Tyrese Maxey is averaging 2.9 3-pointers over his last 12 games.




76ers vs Lakers ATS Pick: 76ers +7½

Philadelphia and Los Angeles are tough to bet online given their injuries. In the 76ers’ case, they are crawling toward the postseason and are 3-6 in their last nine games. Not only is Embiid out but key players such as Robert Covington and De’Anthony Melton are as well. Tobias Harris, a 20-point scorer, is banged up.

But the Lakers are also missing several players possibly including LeBron James, who is dealing with an ankle injury. The Lakers have failed to consistently win games. They edged Minnesota and Milwaukee but also lost to Golden State and Sacramento (twice). The 76ers are a tier below these teams at their current standing.

But Los Angeles has also had difficulty to cover spreads greater than seven points. Our NBA pick is not so much a vote of confidence on Philadelphia, but a fade on the Lakers.



76ers vs Lakers O/U Pick: Over 224

Short-handed teams can have higher-scoring games than the NBA odds intend. We saw this when Boston and Milwaukee played each other on Thursday. Even if James and Harris don’t play, the total of 224 is a tad too low. So it’s better to bet this game to go over.



76ers vs Lakers Player Prop Pick: Tyrese Maxey Over 3s

Maxey will continue to be the offensive engine for the 76ers. He was held to just six points in the last game but we fully expect him to pour it in for this game. His scoring props including his points and 3-pointers are the best NBA prop bets for March 22. Bet the over.

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76ers vs Lakers Game Prediction

Los Angeles Lakers 118 Philadelphia 76ers 113




Questions Of The Day

Which team is most likely to hit the most 3-pointers between the 76ers and Lakers?

The 76ers average slightly more 3-pointers per game (11.6) than the Lakers (11.5).

What is the best point spread bet between Philadelphia and Los Angeles?

Philadelphia +7½ is worth betting in this matchup.

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