2021 NFL Matchup Schedule
| Date | Time ( ET) | NFL Matchup |
| Thursday, October 14th | 6:20 PM | Tampa Bay Buccaneers vs Philadelphia Eagles |
| Sunday, October 17th | 11:00 AM | Miami Dolphins vs Jacksonville Jaguars |
| Sunday, October 17th | 11:00 AM | Kansas City Chiefs vs Washington Football Club |
| Sunday, October 17th | 11:00 AM | Los Angeles Rams vs New York Giants |
| Sunday, October 17th | 11:00 AM | Houston Texans vs Indianapolis Colts |
| Sunday, October 17th | 11:00 AM | Cincinnati Bengals vs Detroit Lions |
| Sunday, October 17th | 11:00 AM | Green Bay Packers vs Chicago Bears |
| Sunday, October 17th | 11:00 AM | Los Angeles Chargers vs Baltimore Ravens |
| Sunday, October 17th | 11:00 AM | Minnesota Vikings vs Carolina Panthers |
| Sunday, October 17th | 2:25 PM | Arizona Cardinals vs Cleveland Browns |
| Sunday, October 17th | 2:25 PM | La Vegas Raiders vs Denver Broncos |
| Sunday, October 17th | 2:25 PM | Dallas Cowboys vs New England Patriots |
| Sunday, October 17th | 6:20 PM | Seattle Seahawks vs Pittsburgh Steelers |
| Monday, October 18th | 6:15 PM | Buffalo Bills vs Tennessee Titans |
| Date | Time ( ET) | NFL Matchup |
| Thursday, October 21st | 6:20 PM | Denver Broncos vs Cleveland Browns |
| Sunday, October 24th | 11:00 AM | Carolina Panthers vs New York Giants |
| Sunday, October 24th | 11:00 AM | New York Jets vs New England Patriots |
| Sunday, October 24th | 11:00 AM | Kansas City Chiefs vs Tennessee Titans |
| Sunday, October 24th | 11:00 AM | Washington Football Team vs Green Bay Packers |
| Sunday, October 24th | 11:00 AM | Atlanta Falcons vs Miami Dolphins |
| Sunday, October 24th | 11:00 AM | Cincinnati Bengals vs Baltimore Ravens |
| Sunday, October 24th | 2:05 PM | Detroit Lions vs Los Angeles Rams |
| Sunday, October 24th | 2:05 PM | Philadelphia Eagles vs las Vegas Raiders |
| Sunday, October 24th | 2:25 PM | Houston Texans vs Arizona Cardinals |
| Sunday, October 24th | 2:25 PM | Chicago Bears vs Tampa Bay Buccaneers |
| Sunday, October 24th | 6:20 PM | Indianapolis Colts vs San Francisco 49ers |
| Monday, October 25th | 6:15 PM | New Orleans Saints vs Seattle Seahawks |
| Date | Time ( ET) | NFL Matchup |
| Thursday, November 4th | 6:20 PM | New York Jets vs Indianapolis Colts |
| Sunday, November 7th | 12:00 PM | Atlanta Falcons vs New Orleans Saints |
| Sunday, November 7th | 12:00 PM | Denver Broncos vs Dallas Cowboys |
| Sunday, November 7th | 12:00 PM | New England Patriots vs Carolina Panthers |
| Sunday, November 7th | 12:00 PM | Minnesota Vikings vs Baltimore Ravens |
| Sunday, November 7th | 12:00 PM | Cleveland Browns vs Cincinnati Bengals |
| Sunday, November 7th | 12:00 PM | Buffalo Bills vs Jacksonville Jaguars |
| Sunday, November 7th | 12:00 PM | Houston Texans vs Miami Dolphins |
| Sunday, November 7th | 12:00 PM | Las Vegas Raiders vs New York Giants |
| Sunday, November 7th | 3:05 PM | Los Angeles Chargers vs Philadelphia Eagles |
| Sunday, November 7th | 3:25 PM | Green Bay Packers vs Kansas City Chiefs |
| Sunday, November 7th | 2:25 PM | Arizona Cardinals vs San Francisco 49ers |
| Sunday, November 7th | 7:20 PM | Tennessee Titans vs Los Angeles Rams |
| Monday, November 8th | 7:15 PM | Chicago Bears vs Pittsburgh Steelers |
| Date | Time ( ET) | NFL Matchup |
| Thursday, December 2nd | 7:20 PM | Dallas Cowboys vs New Orleans Saints |
| Sunday, December 5th | 12:00 PM | New York Giants vs Miami Dolphins |
| Sunday, December 5th | 12:00 PM | Indianapolis Colts vs Houston Texans |
| Sunday, December 5th | 12:00 PM | Minnesota Vikings vs Detroit Lions |
| Sunday, December 5th | 12:00 PM | Philadelphia Eagles vs New York Jets |
| Sunday, December 5th | 12:00 PM | Denver Broncos vs Kansas City Chiefs |
| Sunday, December 5th | 12:00 PM | Arizona Cardinals vs Chicago Bears |
| Sunday, December 5th | 12:00 PM | Los Angeles Chargers vs Cincinnati Bengals |
| Sunday, December 5th | 12:00 PM | Tampa Bay Buccaneers vs Atlanta Falcons |
| Sunday, December 5th | 3:05 PM | Washington Football Team vs Las Vegas Raiders |
| Sunday, December 5th | 3:25 PM | Jacksonville Jaguars vs Los Angeles Rams |
| Sunday, December 5th | 3:25 PM | Baltimore Ravens vs Pittsburgh Steelers |
| Sunday, December 5th | 7:20 PM | San Francisco 49ers vs Seattle Seahawks |
| Monday, December 6th | 7:15 PM | New England Patriots vs Buffalo Bills |
| Date | Time ( ET) | NFL Matchup |
| Thursday, December 9th | 8:20 PM | Pittsburgh Steelers vs Minnesota Vikings |
| Sunday, December 12th | 1:00 PM | Dallas Cowboys vs Washington Football Team |
| Sunday, December 12th | 1:00 PM | San Francisco 49ers vs Cincinnati Bengals |
| Sunday, December 12th | 1:00 PM | Jacksonville Jaguars vs Tennessee Titans |
| Sunday, December 12th | 1:00 PM | Seattle Seahawks vs Houston Texans |
| Sunday, December 12th | 1:00 PM | Las Vegas Raiders vs Kansas City Chiefs |
| Sunday, December 12th | 1:00 PM | New Orleans Saints vs New York Jets |
| Sunday, December 12th | 1:00 PM | Atlanta Falcons vs Carolina Panthers |
| Sunday, December 12th | 1:00 PM | Baltimore Ravens vs Cleveland Browns |
| Sunday, December 12th | 4:05 PM | New York Giants vs Los Angeles Chargers |
| Sunday, December 12th | 4:25 PM | Detroit Lions vs Denver Broncos |
| Sunday, December 12th | 4:25 PM | Buffalo Bills vs Tampa Bay Buccaneers |
| Sunday, December 12th | 8:20 PM | Chicago Bears vs Green Bay Packers |
| Monday, December 13th | 8:15 PM | Los Angeles Rams vs Arizona Cardinals |
| Date | Time ( ET) | NFL Matchup |
| Saturday, January 15th | 4:30 PM | Las Vegas Raiders at Cincinnati Bengals |
| Saturday, January 15th | 8:15 PM | New England Patriots at Buffalo Bills |
| Sunday, January 16th | 1:00 PM | Philadelphia Eagles at Tampa Bay Buccaneers |
| Sunday, January 16th | 4:30 PM | San Francisco 49ers at Dallas Cowboys |
| Sunday, January 16th | 8:15 PM | Pittsburgh Steelers at Kansas City Chiefs |
| Monday, January 17th | 8:15 PM | Arizona Cardinals at Los Angeles Rams |
