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Cardinals vs Rams Prediction, Game Preview, Live Stream, Odds & Picks

In the preseason, we had this game marked as one to watch. The reigning Super Bowl champion Los Angeles Rams taking on the talented and always dangerous Arizona Cardinals. Now, as the Week 10 game approaches, we’re left wanting more from these teams fighting just to make the playoffs.

A loss here would likely end any chance either NFC West team has of earning a Wild Card berth. A win may not matter in the long run as each team has dug itself a large hole from which to escape.

Cardinals vs Rams Odds, Game Preview, Live Stream, Picks & Predictions
Cardinals vs Rams Odds, Game Preview, Live Stream, Picks & Predictions

Let’s check the latest NFL odds, stats, injury reports, and NFL lines for Cardinals vs Rams. We’ve plenty of Vegas NFL odds and NFL week 10 picks for you to consider.

Cardinals a Terrible Second-Half Team

There are several reasons to fade the Cardinals moving forward. Take your pick between a terrible defense, inconsistent quarterback play or gobs of penalty yards they give away. As for me, I will continue to fade Arizona for as long as Kliff Kingsbury is in charge.

There is a clear delineation between Kingsbury’s record in Weeks 1-7 of the NFL season and anything that happens after that. Since Kingsbury took over, the Cardinals are 13-5-1 in the first half of the season but 9-18 from Week 8 onward. This is nothing new for Kingsbury. Combine his time as the Texas Tech head coach, and his record in the first half is 40-20-1 versus 16-43 down the stretch.

The trend is already working its magic in 2022, with the Cardinals 0-2 since Week 8. The only real difference is they stunk before the halfway point and have no clear path back to the playoffs. The wheels are about to fall off, and we’re not going to get caught under this wreck when they do.

Rams in Spiral

Last season, this would be one of the most anticipated matchups of the year. In 2022, we’re watching two disappointments barely in contention for a Wild Card. For as bad as the Cardinals have been, the Rams may be in an even worse state. The reigning champs are 1-4 straight up and against the spread in their last five games. At home, the Rams are 1-4 ATS and 1-3 as home favorites.

This once-promising offense enters Week 10 ranked 29th in scoring and 32nd in yards per play. Are they suffering from a severe Super Bowl hangover, or was the loss of Odell Beckham Jr. that bad? We likely won’t know, as there is no shot OBJ signs with a losing team.

The Rams are doing everything wrong on offense, with one of the worst turnover margins in the league and an average of 1.6 giveaways per game.

Cardinals vs Rams Game Injuries

Cardinals vs Rams Head-to-Head

The Rams enter Week 10 with a three-game winning streak against the Cardinals and are 11-1 in the last 12 meetings. The previous meeting, in Week 3, saw LA win 20-12 at Arizona and cover as 3½-point favorites. Arizona last beat LA in 2021 as 3½-point underdogs.

Cardinals vs Rams Game Information

  • Game: Cardinals vs Rams
  • Date: Sunday, Nov. 13
  • Time: 4:25 p.m. ET
  • Location: SoFi Stadium, Inglewood, CA
  • How to watch Cardinals vs Rams? ESPN
    Cardinals vs Rams Live stream: NFL Game Pass

Cardinals vs Rams Betting Lines

Cardinals vs Rams Picks & Prediction

Picking between these two underperforming former contenders is tough. But trust the results of the last time LA and Arizona clashed. Kyer Murray managed 314 yards passing, but the Cardinals failed to score an offensive touchdown. It was another case of Murray failing to beat the Rams after a disaster in the 2021 playoffs. Murray went 19 of 34 in that game with 137 yards and two interceptions.

The Rams are Murray’s Everest, and he’s not making it to the apex this time.

The Arizona Cardinals are listed at +105 in our Vegas NFL lines. This means that if you wager $100 on the Cardinals, you have a chance to win $105. The Los Angeles Rams are -125, offering a chance to win $80 on a $100 wager.

The implied probability attached to the betting lines gives the Cardinals a 48.78% chance to win, with the Rams at 55.56%.

“The odds and predictions in the article are based on time of writing and publication. They may differ as to when the actual event takes place.”

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