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Packers vs Bills Prediction, Game Preview, Live Stream, Odds & Picks

Rodgers & Co. Huge Underdogs

Before the season started, the Green Bay Packers at the Buffalo Bills looked to be one of the best games of the season on Sunday night football odds. Having lost three consecutive games as favorites, the Packers aren’t accommodating.

Green Bay (3-4) needs to gather itself in a hurry. Waltzing into one of the NFL’s loudest stadiums against the solid Super Bowl favorite is horrible timing. Buffalo (5-1) will look to dismantle another team in prime time, as it did previously against both the Los Angeles Rams (31-10) and Tennessee Titans (41-7). Buffalo had its bye last week.

Packers vs Bills Odds, Game Preview, Live Stream, Picks & Predictions
Packers vs Bills Odds, Game Preview, Live Stream, Picks & Predictions

Let’s check the latest NFL odds, stats, injury reports, and NFL lines for the Packers vs Bills. We’ve plenty of Vegas NFL odds for you to consider.

Run the Ball, Pack

The Green Bay Packers season has been a truly disappointing one, having underachieved in nearly every area. Seemingly nothing has gone right. The defense isn’t anywhere close to where it needs to be, a struggling run game, and quarterback Aaron Rodgers has looked pedestrian regularly. Green Bay has to right itself quickly or its playoff chances will evaporate.

Despite inconsistent play out of its wide receivers, the Packers have thrown the ball 61.47% of the time, 12th in the NFL. Entering the season, Green Bay was expected to be run-heavy, leaning on its rush duo of Aaron Jones and AJ Dillon. Statistically, the run game is averaging 4.6 yards per carry (14th in the league). compared to 6.1 yards per pass attempt (24th). While lacking a down-the-field passing threat, Rodgers hasn’t played like himself, either, Green Bay isn’t balanced. In last Sunday’s 23-21 loss at the Washington Commanders, the Packers ran it just a dozen times.

In losing three games in a row, Green Bay hasn’t played to its strengths, areas worse than expected. Jones and Dillon are still finding success more times than not here. Also, with the defense’s inconsistent play, controlling the clock and keeping that unit fresh wouldn’t hurt.

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Buffalo is Dominant Everywhere

What’s not to like about the Buffalo Bills? They’re a complete team with an elite unit on both sides of the ball. The Bills rank first in yards per game as well as second in points. Defensively, they lead the NFL in the fewest points and yards per game. This is unheard of in the NFL. In other words, Buffalo is stacked.

Quarterback Josh Allen is the +125 MVP favorite. Wide receiver Stefon Diggs has continued to dominate, and Gabriel Davis is producing big plays down the field. While the run game may not get its share of attention, it’s been solid (4.8 yards/carry, 10th in NFL). Dating to last season, running back David Singletary has been solid.

— Buffalo Fanatics (@BfloFanatics) October 3, 2022

Buffalo’s off-season investment in the pass rush has paid off handsomely, with 19 sacks thus far (sixth in NFL). Von Miller (six sacks) has been worth every penny to date. His two-sack performance was critical in the 24-20 win at the Kansas City Chiefs. The secondary also figures to improve when All-Pro cornerback Tre’Davious White returns (ACL injury). White won’t play this week, but he is inching closer to action.

Packers vs Bills Game Injuries

Packers vs Bills Head-to-Head

Since 2006, the series is tied, each team with two wins. Green Bay has never won in Buffalo (0-6), having lost every game by at least a touchdown.

Packers vs Bills Game Information

  • Game: Packers (3-4) vs Bills (5-1)
  • Date/Time: Sunday, Oct. 30th, 8:20 p.m. ET
  • Location: Highmark Stadium, Orchard Park, NY
  • How to watch Packers vs Bills? ESPN
    Packers vs Bills Live stream: NFL Game Pass

Take a Look at Other Previews, Picks & Predictions For NFL Sunday Night Football Matchups

Packers vs Bills Betting Lines

Packers vs Bills Prediction

The Bills have an advantage in almost every department against the Packers. Green Bay’s decision to run the ball more often may have to wait a week, as Buffalo boasts the NFL’s best defense against the rush. Rodgers, if protected, can be successful against the Bills’ secondary. However, the Packers’ offensive line has struggled consistently, having surrendered 15 sacks.

Green Bay leads the NFL in passing yards allowed per game, but this is a deceiving stat. Opponents are throwing the ball only 49.38% of plays (second). Buffalo will throw far more often, 63.59% of plays (seventh). Moreover, cornerback Jaire Alexander comes off a rough showing against Washington’s Terry McLaurin.

So, Diggs should have his way. The Bills will once again put the NFL world on notice. Take them minus the points at plus-money.

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“The odds and predictions in the article are based on the time of writing and publication. They may differ as to when the actual event takes place.”

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