Chiefs vs Cardinals Odds, Preview, Stream, Picks & Predictions

A game between the Arizona Cardinals and Kansas City Chiefs is a matchup that sounds great for any week of the regular season as well as for the Super Bowl. We’re talking about two teams with some of the strongest and most exciting offenses in the game, two defenses that are all about dominance and a perfect matchup between one of the bonafide coaching legends in the league, Kansas City’s Andy Reid, and one of the best up and coming, offensive-minded young coaches in the league Kliff Kingsbury. So, what does this all add up to? Of course, one of the best matchups to watch for in the first week of the 2022 season.

Let’s check the latest NFL picks, news, stats, injury reports, and NFL expert picks for Chiefs vs Cardinals. We’ve plenty of NFL predictions for you to consider.

But until week 1 of the upcoming season pops around, let’s take a look back at the last time both of these teams squared up, back in 2018 at Arrowhead Stadium in Kansas City. That day, Patrick Mahomes, who back then was playing in his first full season as a starter, a season that ended up seeing him take home the led the Chiefs offense to a strong and hard fought 26-14 win against Josh Rosen, former Cardinals QB with a career that has seen him become the shadow of a shadow of what he was originally pitted out to be.

With 249 passing yards and two touchdown passes to former Chiefs star WR Tyreek Hill the Chiefs managed to outlast the Cardinals at home in a game that saw former Arizona Cardinals legendary WR Larry Fitzgerald pass Terrell Owens for 2nd all-time in the league’s career receiving yards list. This game allowed the Chiefs to inch closer and closer to finishing the season with the No.1 seed in the playoffs, a feat that would end up leading the Chiefs to their first AFC Championship game at home in Arrowhead Stadium, where they would end up losing to Tom Brady and the Patriots.

With the new season coming, the Cardinals now with Kyler Murray at QB but without DeAndre Hopkins who will be out with a six-game suspension and the Chiefs, with Patrick Mahomes back at it, but this time without Tyreek Hill, now with the Dolphins will surely put on a show-stopping matchup in Arizona, where the Chiefs should be able to edge out the Cardinals just enough to score their first win of the season.

Chiefs vs Cardinals Game Information

Game: Chiefs vs Cardinals
Location: State Farm Stadium. Glendale, Arizona.
Day/Time: Sunday, September 11th, 4:25 p.m. ET
Chiefs vs Cardinals Live Stream: NFL Game Pass

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Chiefs vs Cardinals Odds

“The odds and predictions in the article are based on the time of writing and publication. They may differ as to when the actual event takes place.”