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Rams vs Cardinals Prediction, Game Preview, Live Stream, Odds & Picks

Early Showdown Between NFC West Rivals

The surging Arizona Cardinals look to build off their epic comeback against the Las Vegas Raiders by taking out their divisional rival, the Los Angeles Rams. This will be a measure of revenge for the Cardinals too as the Rams humiliated them in the playoffs last season. But the NFL betting odds still favor Los Angeles despite all the circumstances surrounding the team.

Let’s check the latest NFL odds, stats, injury reports, and NFL lines for Rams vs Cardinals. We’ve plenty of Vegas NFL odds for you to consider.

Rams vs Cardinals Odds, Game Preview, Live Stream, Picks & Predictions
Rams vs Cardinals Odds, Game Preview, Live Stream, Picks & Predictions

Rams Still Trying to Find Form

Los Angeles Rams beat the Atlanta Falcons last week as they should have. However, they failed to cover as their defense coughed up 17 points in the fourth quarter. Cooper Kupp remains an elite receiver and was responsible for half of the Rams’ touchdowns. But Matthew Stafford continues to struggle.

Stafford threw another pair of picks as he leads the NFL in interceptions with five. He can’t afford to stay turnover-prone as the Rams have the second-most in the NFL. The running game also needs a boost as the Rams have just 117 yards through two games but have allowed 211.

Against Arizona, the Rams are facing a team they’ve owned for the most part. They’ll need to get to an early lead as they did against Atlanta. Arizona has given up the second-most passing yards and touchdowns. It’s possible to bet online on Stafford to light it up here.

Can the Cardinals Maintain Momentum?

After six quarters of getting disrespected, the Arizona Cardinals’ defense finally woke up against the Raiders. Arizona clamped down against Las Vegas and limited it to just three points, giving Kyler Murray and the offense all the time to mount a 20-point comeback.

Murray led his team to the win but he’s been just “aite” this season. Against the Rams, Murray will need to recapture his form from the first half of last season where he and the Cardinals dropped 37 points in SoFi Stadium. The two-time Pro Bowler was efficient in this win and he’ll need to be.

Going back to last season, the Cardinals are 8-0 when Murray has a passer rating over 100 but only 2-7 when he doesn’t. The offensive line is one of the oldest in the NFL and will need to keep it together. Fortunately for them, the Rams’ pass rush has not been the same. The unit has the third-lowest pressure rate so that could bode well for Arizona.

Rams vs Cardinals Head-to-Head

The Cardinals’ win at SoFi last season is their only one against the Rams in the Sean McVay era. Los Angeles is also 8-1-1 against the spread (ATS) in this span and has nearly doubled Arizona’s points: 30.2 to 16.2 per game. The total has gone over in four of their last six games.

Rams vs Cardinals Game Injuries

Rams vs Cardinals Game Information

  • Date: Sunday, Sept. 25
  • Time: 4:25 p.m. ET
  • Location: State Farm Stadium, Glendale, AZ
  • How to watch Rams vs Cardinals? ESPN, FOX
    Rams vs Cardinals Live stream: NFL Game Pass

Rams vs Cardinals Betting Lines

Rams vs Cardinals Prediction

Some say momentum is not a thing in the NFL. We don’t believe that, especially not with the hot-and-cold Cardinals. This is a team that went on both winning streaks and losing streaks. Now, the team is turning up and will carry that momentum back to the desert. Murray is due for a big game and he can do that against the Rams’ reeling defense.

Give us the +155 on Arizona on the online sportsbook happily. Additionally, the over 48½ is another decent bet as this one could have fireworks given the inconsistent play on defense.

“The odds and predictions in the article are based on the time of writing and publication. They may differ as to when the actual event takes place.”

Rams vs Cardinals Edge

Rams vs Cardinals Results

Rams vs Cardinals Game Summary


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