49ers vs Titans Game Preview, Odds, Stats & Injuries

San Francisco 49ers vs Tennessee Titans News & Picks

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49ers vs Titans Odds

The San Francisco 49ers (8-6) head to Music City on Thursday night to take on the Tennessee Titans (9-5) in Week 16 at Nissan Stadium.

The 49ers picked up a win at home against the Atlanta Falcons 31-13 last week, while the Titans fell on the road to the Pittsburgh Steelers 19-13. Early NFL odds have San Francisco as the -3½ favorite, with the point total at 44½.

San Francisco has positioned themselves back in the NFC playoff hunt with five wins in its last six contests averaging 29.2 points over that stretch.

Against the Falcons in Week 15, the 49ers dominated, scoring on four straight drives. Jimmy Garoppolo threw for 235 yards and a touchdown while the running game added 162 yards on the ground and three touchdowns.

Defensively, the 49ers held the Falcons to 13 points, grabbed three sacks, and are allowing just 22.4 points per game. San Francisco now ranks sixth in the league in total defense (321.8) and sixth against the pass (213.2).

The Titans will prepare for their Week 16 tilt against the 49ers after a second-half collapse against the Steelers. The offense was shut out and turned the ball over three times in the second half en route to their fifth loss.

Despite their lack of weaponry, the Titans have found ways to win thanks to their running back tandem. Although they’ve been without star back Derrick Henry, D’Onta Foreman and Dontrell Hilliard have combined for over 150 yards twice in the last three games.

On the defensive side of the ball, the Titans’ defense held the Steelers to 168 total yards, including just 35 yards rushing, while sacking Ben Roethlisberger three times. Despite not recording a turnover, Tennessee’s defense has looked solid, holding opponents to 329.2 yards and 22.1 points per game.

We know you love night games, and that’s why BetUS brings you the best NFL Odds for Thursday, Sunday and Monday’s Night games. For this week, in addition to this matchup, we have in the menu Washington vs Cowboys & Dolphins vs Saints for you to consider.

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